Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 85.7%High 1 · 14.3%

Etomidate vs all other induction agents

All‐cause mortality · patients with endotracheal intubation in critically ill patients

Etomidate showed no clear difference in mortality compared with all other induction agents (moderate certainty).

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
OR 1.17 [0.86, 1.6]
6 studies · 772 participants
Moderate

Etomidate vs all other induction agents

ACTH stimulation test ACTH stimulation test is considered positive if the change in serum cortisol level was less than 9 μg/dL (248 nmol/L) after the administration of 250 μg of cosyntropin · patients with endotracheal intubation in critically ill patients

Etomidate probably leads to higher ACTH stimulation test ACTH stimulation test is considered positive… compared with all other induction agents (moderate certainty).

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
OR 2.37 [1.61, 3.47]
3 studies · 519 participants
Moderate

Etomidate vs all other induction agents

Random serum cortisol levels (μg/dL) after receiving intervention · patients with endotracheal intubation in critically ill patients

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 105 participants
Moderate

Etomidate vs all other induction agents

Organ system dysfunction (during admission) · patients with endotracheal intubation in critically ill patients

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 469 participants
High

Etomidate vs all other induction agents

Duration of ICU stay · patients with endotracheal intubation in critically ill patients

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 621 participants
Moderate

Etomidate vs all other induction agents

Length of hospital stay · patients with endotracheal intubation in critically ill patients

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 152 participants
Moderate

Etomidate vs all other induction agents

Duration of mechanical ventilation · patients with endotracheal intubation in critically ill patients

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 621 participants
Moderate