Relief of pain · participants with painful obstructive chronic pancreatitis
Endoscopy probably leads to higher pain relief ‐ middle‐term compared with surgery (moderate certainty).
2 findings from 1 review
Major complications and mortality · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Quality of Life: SF‐36 (physical component) · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Health‐related quality of life (mental) · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Endocrine pancreatic insufficiency (new onset) ‐ long‐term · participants with painful obstructive chronic pancreatitis
Endoscopy showed no clear difference in endocrine pancreatic insufficiency (new onset) ‐ long‐term compared with surgery (low certainty).
1 finding from 1 review
Exocrine pancreatic insufficiency (new onset) · participants with painful obstructive chronic pancreatitis
Endoscopy showed no clear difference in exocrine pancreatic insufficiency (new onset) ‐ long‐term compared with surgery (moderate certainty).
1 finding from 1 review
Proportion of participants with stigmata of recent haemorrhage at index endoscopy · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment showed no clear difference in proportion of participants with stigmata of recent haemorrhage at… compared with H2RA, placebo or no treatment (low certainty).
1 finding from 1 review
Endoscopic haemostatic treatment at index endoscopy · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment probably leads to lower endoscopic haemostatic treatment at index endoscopy compared with H2RA, placebo or no treatment (moderate certainty).
1 finding from 1 review
Recurrent and persistent bleeding overall rates with or without second‐look endoscopy Rebleeding (persistent or recurrent bleeding) · patients with high‐risk bleeding ulcers
Epinephrine probably leads to lower recurrent and persistent bleeding overall rates with or without… compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Adverse effects of endoscopy therapy Adverse effects · patients with high‐risk bleeding ulcers
Epinephrine probably leads to higher adverse effects of endoscopy therapy Adverse effects compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Intervention not reported
PPI versus placebo · patients with heartburn remission in endoscopy negative reflux disease
The intervention probably leads to lower PPI versus placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
H2RA versus placebo · patients with heartburn remission in endoscopy negative reflux disease
The intervention probably leads to lower H2RA versus placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
PPI versus H2RA · patients with heartburn remission in endoscopy negative reflux disease
The intervention may leads to lower PPI versus H2RA (low certainty).
1 finding from 1 review
Intervention not reported
PPI versus prokinetic · patients with heartburn remission in endoscopy negative reflux disease
The intervention may leads to lower PPI versus prokinetic (low certainty).
1 finding from 1 review
UGIH‐related mortality · people with acute UGIH
1 finding from 1 review
All‐cause mortality · people with acute UGIH
It is very uncertain whether erythromycin plus nasogastric tube lavage changes all‐cause mortality compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).
1 finding from 1 review
Visualisation of gastric mucosa · people with acute UGIH
1 finding from 1 review
NSAEs · people with acute UGIH
It is very uncertain whether erythromycin plus nasogastric tube lavage changes NSAEs compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).
1 finding from 1 review
Rebleeding · people with acute UGIH
It is very uncertain whether erythromycin plus nasogastric tube lavage changes rebleeding compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).
1 finding from 1 review
Blood transfusion · people with acute UGIH
1 finding from 1 review