Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,679 questions · 1,720 findings · 335 reviews · Headline outcomes only

No studies found 192 · 11.2%GRADE not reported 75 · 4.4%Very low 526 · 30.6%Low 504 · 29.3%Moderate 305 · 17.7%High 118 · 6.9%

Early vs late supportive care plus ribavirin

Mortality in early versus late supportive care plus ribavirin · people diagnosed with suspected or confirmed Crimean Congo haemorrhagic fever

It is very uncertain whether early changes mortality in early versus late supportive care plus ribavirin compared with late supportive care plus ribavirin (very low certainty).

1 finding from 1 review

Planned early birth vs expectant management

Definite early‐onset neonatal sepsis · women with prelabour rupture of membranes at term (37 weeks' gestation or later)

It is very uncertain whether planned early birth changes definite early‐onset neonatal sepsis compared with expectant management (very low certainty).

1 finding from 1 review

Planned early birth vs expectant management

Definite or probable early‐onset neonatal sepsis · women with prelabour rupture of membranes at term (37 weeks' gestation or later)

Planned early birth may leads to lower definite or probable early‐onset neonatal sepsis compared with expectant management (low certainty).

1 finding from 1 review

Early vs delayed open or laparoscopic appendicectomy

Time away from normal activities (days) · paediatric and adult patients with appendiceal phlegmon

It is very uncertain whether early changes time away from normal activities (days) Median compared with delayed open or laparoscopic appendicectomy (very low certainty).

1 finding from 1 review