Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

355 questions · 760 findings · 41 reviews · All outcomes

No studies found 25 · 3.3%GRADE not reported 674 · 88.7%Very low 29 · 3.8%Low 16 · 2.1%Moderate 16 · 2.1%High 0 · 0%

Dual mini-screw implant vs Single mini-screw implant

Residual overjet at the end of treatment · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Caries distribution assessment (individual, tooth and surface levels) vs None (descriptive prevalence review; subgroup analyses by urban/rural status, country and year)

Caries distribution (individual/tooth/surface level) · European adolescents aged 12–19 years

Caries distribution was skewed at individual, tooth and surface levels and too heterogeneous to meta-analyze (narrative synthesis of 11 studies; not GRADE-rated).

1 finding from 1 review

Tooth- and tissue-supported removable partial denture: dual-impression technique with a different material vs An alternative dual-impression technique with a different material

Outcome not reported · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture

The review found no eligible studies for this question.

1 finding from 1 review

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Perceptual speech assessment: residual post-operative velopharyngeal insufficiency · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate
1 finding from 1 review
  • Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
    3 months post-operatively
    Five (14%) of the participants in group 1 (MIPP) and four (11%) in group 2 had residual post-operative velopharyngeal insufficiency, P > 0.05. The report provided no details on post-operative speech assessment other…
    1 study · 72 participants
    GRADE not reported

Dual mini-screw implant vs Single mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in success of the anchorage device compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Duration of space closure · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in duration of space closure compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Mesiodistal movement of the upper first permanent molar · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant led to higher mesiodistal movement of the upper first permanent molar compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Dual zinc + arginine dentifrice vs Control (regular fluoride) dentifrice

Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether dual zinc + arginine dentifrice changes dentist-reported OLT hedonic rating (scale 1 to 9) compared with control (regular fluoride) dentifrice (very low certainty).

1 finding from 1 review

Monotherapy or dual antiretroviral therapy vs No antiretroviral medication (treatment-naive)

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

Oral candidiasis prevalence did not differ significantly between treatment-naive CLWH and those on monotherapy or dual therapy (very low certainty).

1 finding from 1 review

Individualised homeopathic medicine (two doses over 24 hours) vs placebo

Ulcer healing · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Individualised homeopathic medicine (two doses over 24 hours) led to higher complete ulcer healing by end of study (day 6) compared with placebo; GRADE not reported.

1 finding from 1 review

Individualised homeopathic medicine (two doses over 24 hours) vs placebo

Mean pain score and mean ulcer size · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

Individualised homeopathic medicine (two doses over 24 hours) vs placebo

Pain free by end of study (day 6) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Individualised homeopathic medicine (two doses over 24 hours) led to higher pain free by end of study (day 6) compared with placebo; GRADE not reported.

1 finding from 1 review

Individualised oral care plan based on a multidisciplinary assessment vs usual care

Plaque · Adults aged 22 to 57 years with mixed levels of ID; setting residential
1 finding from 1 review
  • Oral hygiene interventions for people with intellectual disabilities 2019 · Cochrane All outcomes
    Medium term (6 weeks to 12 months)
    Individualised oral care plan vs usual care. Subjective Oral Hygiene Rating scale 1-5 and Improvement Differential, mean 12 months; SOHR 2.97 (intervention) vs 3.10 (control); improvement differential 38% vs 5%; 79…
    1 study · 79 participants
    Very low

Partial caries removal (single stage; residual dentinal caries sealed into the tooth definitively) vs Complete caries removal

Pulp exposure during caries removal · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

Partial caries removal (single stage; residual dentinal caries… probably leads to lower pulp exposure during caries removal compared with complete caries removal (moderate certainty).

1 finding from 1 review

Partial caries removal (single stage; residual dentinal caries sealed into the tooth definitively) vs Complete caries removal

Restoration failure · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

It is very uncertain whether partial caries removal (single stage; residual dentinal caries… changes failure of restorations compared with complete caries removal (very low certainty).

1 finding from 1 review