Participant preference ‐ wish to use drug in next treatment · cancer patients
Olanzapine showed no clear difference in participant preference ‐ wish to use drug in next treatment compared with placebo/no treatment (moderate certainty).
1 finding from 1 review
RR 1.43 [0.97, 2.09]
Studies not reported
Moderate
Parasympathomimetic drugs (choline esters, cholinesterase inhibitors) vs No treatment
Outcome not reported · Patients with radiation-induced salivary gland dysfunction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Adverse effects (side effects; treatment withdrawals) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Johnson 1993 (5 mg tds): sweating 37%, headache 15%, urinary frequency 14%, vasodilatation 12%, dizziness 10%, dyspepsia 10%, nausea 8%, asthenia 8%, diarrhoea 5%; 6% withdrew at 5 mg tds and 29% at 10 mg tds. LeVeque…
2 studies · 278 participants
GRADE not reported
Adverse effects (side effects; treatment withdrawals) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Davies 1994: main side effects with pilocarpine were nausea 20%, sweating 15%, lacrimation 10%. One participant definitely withdrew because of side effects; another may have.
1 study · 20 participants
GRADE not reported
Participant‐reported pain relief of 30% or greater · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Participant‐reported pain relief of 50% or greater · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Patient Global Impression of Change much or very much improved · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Any pain‐related outcome indicating some improvement · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number experiencing adverse effects · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of participants experiencing any serious adverse events · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Withdrawals due to adverse events · adults with fibromyalgia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Appetite improvement compared to other drugs Questionnaire of appetite rating · cachexia anorexia syndrome
The intervention showed no clear difference in appetite improvement compared to other drugs Questionnaire of… (low certainty).
1 finding from 1 review
Intervention not reported
Weight improvement compared to other drugs % of patients that improved their weight in kg · cachexia anorexia syndrome
It is very uncertain whether the intervention changes weight improvement compared to other drugs % of patients that… (very low certainty).
1 finding from 1 review
Intervention not reported
Pain freedom at 2 h · acute treatment of migraine in children
The intervention led to higher pain freedom at 2 h; GRADE not reported.
1 finding from 1 review
Intervention not reported
Adverse events · acute treatment of migraine in children
The intervention showed no clear difference in adverse events; GRADE not reported.
1 finding from 1 review
Intervention not reported
Pain freedom at 2 h · acute treatment of migraine in children
The intervention probably leads to higher pain freedom at 2 h (moderate certainty).
1 finding from 1 review
Intervention not reported
Adverse events · acute treatment of migraine in children
The intervention showed no clear difference in adverse events (moderate certainty).
1 finding from 1 review
Intervention not reported
Pain freedom at 2 h · acute treatment of migraine in adolescents
The intervention probably leads to higher pain freedom at 2 h (moderate certainty).
1 finding from 1 review
Intervention not reported
Adverse events · acute treatment of migraine in adolescents
The intervention probably leads to higher adverse events (moderate certainty).
1 finding from 1 review
Intervention not reported
Pain freedom at 2 h · acute treatment of migraine in adolescents
The intervention probably leads to higher pain freedom at 2 h (moderate certainty).
1 finding from 1 review