Adverse effects (non‐serious) · participants with hidradenitis suppurativa
Topical clindamycin showed no clear difference in adverse effects (non‐serious) compared with placebo (moderate certainty).
1 finding from 1 review
HRQOL RosaQoL · Participants with rosacea
1 finding from 1 review
Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
Proportion of participants with adverse event · Participants with rosacea
Clindamycin phosphate 1.2% + tretinoin 0.025% gel probably leads to higher proportion of participants with adverse event compared with placebo (moderate certainty).
1 finding from 1 review
Physician‐assessed improvement in rosacea severity · Participants with rosacea
1 finding from 1 review
Assessment of erythema or telangiectasia · Participants with rosacea
Clindamycin phosphate 1.2% + tretinoin 0.025% gel showed no clear difference in assessment of erythema or telangiectasia compared with placebo (moderate certainty).
1 finding from 1 review
Lesion count · Participants with rosacea
1 finding from 1 review
Time needed until improvement of the skin lesions · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
Duration of remission ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
Participant's global self‐assessment of improvement (long‐term data) · participants with acne
Benzoyl peroxide showed no clear difference in participant's global self‐assessment of improvement (long‐term data) compared with clindamycin (low certainty).
1 finding from 1 review
Adverse effects (side effects; treatment withdrawals) · participants with acne
It is very uncertain whether benzoyl peroxide changes withdrawal due to adverse effects (long‐term data) Treatment… compared with clindamycin (very low certainty).
1 finding from 1 review
Total number of participants with any adverse events (long‐term data) Treatment duration: range 10 weeks to 12 weeks · participants with acne
Benzoyl peroxide showed no clear difference in total number of participants with any adverse events (long‐term… compared with clindamycin (moderate certainty).
1 finding from 1 review
Treatment withdrawal · participants with acne
Azelaic acid showed no clear difference in withdrawal for any reason (long term: treatment duration > 8 weeks) compared with clindamycin (low certainty).
1 finding from 1 review
Minor adverse events · participants with acne
Azelaic acid showed no clear difference in total number of participants who experienced at least one minor… compared with clindamycin (low certainty).
1 finding from 1 review
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawal for any reason (medium term: treatment duration from 5 to 8 weeks) · participants with acne
Nicotinamide showed no clear difference in withdrawal for any reason (medium term: treatment duration from 5 to… compared with clindamycin (low certainty).
1 finding from 1 review
Minor adverse events · participants with acne
Nicotinamide showed no clear difference in total number of participants who experienced at least one minor… compared with clindamycin (low certainty).
1 finding from 1 review
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks) · participants with acne
Azelaic acid showed no clear difference in participants' global self‐assessment of acne improvement Good or… compared with clindamycin (low certainty).
1 finding from 1 review