Microbiological cure · Pregnant women with a confirmed Chlamydia trachomatis infection
Clindamycin may leads to higher microbiological cure compared with placebo (low certainty).
1 finding from 1 review
Microbiological cure · Pregnant women with a confirmed Chlamydia trachomatis infection
Clindamycin showed no clear difference in microbiological cure compared with erythromycin (low certainty).
1 finding from 1 review
Fever index (mean degree‐hour) ‐ all women · patients with septic abortion
1 finding from 1 review
Fever index (mean degree‐hour) ‐ bacteraemic patients · patients with septic abortion
1 finding from 1 review
Length of hospital stay · patients with septic abortion
1 finding from 1 review
Complications · patients with septic abortion
Clindamycin showed no clear difference in complications compared with penicillin plus chloramphenicol compared to for (moderate certainty).
1 finding from 1 review
Percentage of closed pockets · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Antimicrobial resistance · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Clindamycin + SRP showed no clear difference in probing pocket depth compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD -0.14 [-0.82, 0.54]
1 study · 26 participants
GRADE not reported
MD -0.10 [-0.79, 0.59]
1 study · 26 participants
GRADE not reported
MD 0.20 [-0.38, 0.78]
1 study · 26 participants
Very low
Clinical attachment level (CAL) · Adults with aggressive periodontitis
It is very uncertain whether clindamycin + SRP changes clinical attachment level (CAL) compared with doxycycline + SRP (very low certainty).
3 findings from 1 review
MD -0.90 [-1.62, -0.18]
1 study · 23 participants
Very low
MD -0.40 [-1.15, 0.35]
1 study · 23 participants
GRADE not reported
MD 0.50 [-0.26, 1.26]
1 study · 23 participants
GRADE not reported
Patient-reported quality of life changes · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Clindamycin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
3 findings from 1 review
MD -1.30 [-2.14, -0.46]
1 study · 21 participants
GRADE not reported
MD 0.40 [-0.35, 1.15]
1 study · 21 participants
GRADE not reported
MD -1.70 [-2.40, -1.00]
1 study · 21 participants
Very low
Percentage of closed pockets · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Patient-reported quality of life changes · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Clindamycin + SRP showed no clear difference in clinical attachment level (CAL) compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD 0.40 [-0.22, 1.02]
1 study · 26 participants
GRADE not reported
MD 0.20 [-0.55, 0.95]
1 study · 26 participants
Very low
MD 0.10 [-0.60, 0.80]
1 study · 26 participants
GRADE not reported
Probing pocket depth · Adults with aggressive periodontitis
It is very uncertain whether clindamycin + SRP changes probing pocket depth compared with doxycycline + SRP (very low certainty).
3 findings from 1 review
MD -0.80 [-1.58, -0.02]
1 study · 23 participants
Very low
MD 0.20 [-0.36, 0.76]
1 study · 23 participants
GRADE not reported
MD -0.40 [-1.14, 0.34]
1 study · 23 participants
GRADE not reported
Adverse events · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults with aggressive periodontitis
It is very uncertain whether clindamycin + SRP changes probing pocket depth compared with SRP (very low certainty).
3 findings from 1 review
MD -1.80 [-2.47, -1.13]
1 study · 21 participants
Very low
MD -1.10 [-1.94, -0.26]
1 study · 21 participants
GRADE not reported
MD 0.10 [-0.55, 0.75]
1 study · 21 participants
GRADE not reported
Antimicrobial resistance · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review