Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 9 findings · 1 reviews · Epilepsy · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 33.3%High 6 · 66.7%

Flunarizine vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with drug‐resistant epilepsy

Flunarizine showed no clear difference in adverse effects ‐ Blurred vision No of patients with blurred vision compared with placebo (high certainty).

1 finding from 1 review

Nimodipine vs placebo

50% or greater reduction in seizure frequency Number of seizures · patients with drug‐resistant epilepsy

Nimodipine showed no clear difference in 50% or greater reduction in seizure frequency Number of seizures compared with placebo (moderate certainty).

1 finding from 1 review