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What do systematic reviews say?

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Evidence found and GRADE certainty

22 questions · 27 findings · 3 reviews

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No studies found 7 · 25.9%GRADE not reported 0 · 0%Very low 11 · 40.7%Low 4 · 14.8%Moderate 5 · 18.5%High 0 · 0%

Betahistine vs placebo

Tinnitus loudness · patients with subjective idiopathic tinnitus
2 findings from 1 review
  • Betahistine for tinnitus 2018 · Cochrane Headline outcomes only
    no estimate extracted
    2 studies · 81 participants
    Very low
  • Betahistine for tinnitus 2018 · Cochrane Headline outcomes only
    no estimate extracted
    1 study · 70 participants
    Very low

Betahistine vs placebo

Other adverse effects (yes or no) · patients with subjective idiopathic tinnitus
2 findings from 1 review

Betahistine vs placebo

Change in tinnitus loudness measured by a visual analogue scale (range 0 to more than 10) · patients with subjective idiopathic tinnitus
1 finding from 1 review

Betahistine vs placebo

Significant adverse events · patients with subjective idiopathic tinnitus
2 findings from 1 review

Betahistine vs placebo

Change in Tinnitus Severity Index (range 0 to 56) · patients with subjective idiopathic tinnitus
1 finding from 1 review

Betahistine vs placebo

Tinnitus symptom severity · patients with subjective idiopathic tinnitus
1 finding from 1 review

Betahistine vs placebo

Depressive symptoms · patients with subjective idiopathic tinnitus

The review found no eligible studies for this question.

1 finding from 1 review
  • Betahistine for tinnitus 2018 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Betahistine vs placebo

Symptoms of generalised anxiety · patients with subjective idiopathic tinnitus

The review found no eligible studies for this question.

1 finding from 1 review
  • Betahistine for tinnitus 2018 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Betahistine vs placebo

Proportion of patients with improvement according to global judgement of patient subgrouped by diagnosis№ of participants: 606(11 RCTs) · patients with symptoms of vertigo

Betahistine may leads to higher proportion of patients with improvement according to global… compared with placebo (low certainty).

1 finding from 1 review

Betahistine vs placebo

Proportion of patients with adverse effects№ of participants: 819(12 RCTs) · patients with symptoms of vertigo

Betahistine showed no clear difference in proportion of patients with adverse effects№ of participants: 819(12… compared with placebo (low certainty).

1 finding from 1 review

Betahistine vs placebo/no treatment

Improvement in vertigo frequency · Ménière’s disease

It is very uncertain whether betahistine changes improvement in vertigo frequency compared with placebo/no treatment (very low certainty).

2 findings from 1 review