Findings

What do systematic reviews say?

9 questions · 14 findings · 2 reviews · Dementia and Cognitive Improvement

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No studies found 2 · 14.3%GRADE not reported 0 · 0%Very low 1 · 7.1%Low 3 · 21.4%Moderate 8 · 57.1%High 0 · 0%

B vitamins vs placebo

Incidence of dementia ‐ not measured · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

B vitamins vs placebo

Cognitive function · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 488 participants
Very low

B vitamins vs placebo

Cognitive subdomain: episodic memory measured at the end of · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 397 participants
Moderate

B vitamins vs placebo

Executive function (specific cognitive function) · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 392 participants
Moderate

B vitamins vs placebo

Information processing speed · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 173 participants
Moderate

B vitamins vs placebo

Quality of life · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 138 participants
Moderate

B vitamins vs placebo

Mortality ‐ not reported · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

B vitamins vs placebo

Supplementation with beta‐carotene + vit C + vit E Overall cognitive functioning · cognitively healthy people in mid and late life

6 findings from 1 review

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 2556 participants
Moderate
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 317 participants
Low
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 6956 participants
Moderate

Show 3 more findings

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 241 participants
Low
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 3985 participants
Moderate
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 10249 participants
Low

B vitamins vs placebo

Incidence of dementia or MCI · cognitively healthy people in mid and late life

B vitamins showed no clear difference in incidence of MCI or dementia > 2 to 5 years of supplementation compared with placebo (moderate certainty).

1 finding from 1 review

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
RR 0.89 [0.67, 1.18]
1 study · 1803 participants
Moderate