Question · asked by 1 review
B vitamins vs placebo: Supplementation with beta‐carotene + vit C + vit E Overall cognitive functioning
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
B vitamins vs placebo Overall cognitive functioning 3 to 12 months of supplementation (final measurement data) · cognitively healthy people in mid and late life Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid… (2018) · Cochrane Headline outcomes only | no estimate extracted | 3 studies · 2556 participants | Moderate |
B vitamins vs placebo Overall cognitive functioning 3 to 12 months of supplementation (change from baseline data) · cognitively healthy people in mid and late life Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid… (2018) · Cochrane Headline outcomes only | no estimate extracted | 2 studies · 317 participants | Low |
B vitamins vs placebo Overall cognitive functioning > 1 to 2 years of supplementation (final measurement data) · cognitively healthy people in mid and late life Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid… (2018) · Cochrane Headline outcomes only | no estimate extracted | 5 studies · 6956 participants | Moderate |
B vitamins vs placebo Overall cognitive functioning > 1 to 2 years of supplementation (change from baseline data) · cognitively healthy people in mid and late life Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid… (2018) · Cochrane Headline outcomes only | no estimate extracted | 1 study · 241 participants | Low |
B vitamins vs placebo Overall cognitive functioning > 2 to 5 years of supplementation (final measurement data) · cognitively healthy people in mid and late life Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid… (2018) · Cochrane Headline outcomes only | no estimate extracted | 4 studies · 3985 participants | Moderate |
B vitamins vs placebo Overall cognitive functioning ‐ > 5‐10 years of supplementation (final measurement data) · cognitively healthy people in mid and late life Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid… (2018) · Cochrane Headline outcomes only | no estimate extracted | 3 studies · 10249 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.