Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 20 findings · 3 reviews

No studies found 5 · 25%GRADE not reported 0 · 0%Very low 9 · 45%Low 2 · 10%Moderate 0 · 0%High 4 · 20%

Atorvastatin vs placebo

Asthma exacerbations requiring hospitalisation or a course of steroids · people with asthma

The review found no eligible studies for this question.

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Atorvastatin vs placebo

Health‐related quality of life · people with asthma

The review found no eligible studies for this question.

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Atorvastatin vs placebo

Change in morning PEF (L/min) at endpoint · people with asthma

It is very uncertain whether atorvastatin changes lung function: change in morning PEF compared with placebo (very low certainty).

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    MD 12.32
    1 study · 60 participants
    Very low

Atorvastatin vs placebo

Change from baseline in pre‐bronchodilator FEV1 · people with asthma

It is very uncertain whether atorvastatin changes lung function: change in FEV1 (pre) compared with placebo (very low certainty).

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    MD 0.13
    1 study · 60 participants
    Very low

Atorvastatin vs placebo

Lung function: change in FEV1 (post) · people with asthma

It is very uncertain whether atorvastatin changes lung function: change in FEV1 (post) compared with placebo (very low certainty).

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    MD 0.11
    1 study · 60 participants
    Very low

Atorvastatin vs placebo

Serious adverse events or adverse events · people with asthma

The review found no eligible studies for this question.

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Atorvastatin vs placebo

Asthma control · people with asthma

It is very uncertain whether atorvastatin changes asthma control: change in ACQ compared with placebo (very low certainty).

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    MD 0.41
    1 study · 60 participants
    Very low

Intervention not reported

LDL‐cholesterol atorvastatin 10 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 20 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 40 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 80 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

Total testosterone · Male participants
1 finding from 1 review

Intervention not reported

Acronyms and grades · Male participants

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Total testosterone · Adult female participants with PCOS
1 finding from 1 review

Intervention not reported

FAI · Adult female participants with PCOS
1 finding from 1 review

Intervention not reported

SHBG · Adult female participants with PCOS
1 finding from 1 review

Intervention not reported

Androstenedione · Adult female participants with PCOS
1 finding from 1 review

Intervention not reported

DHEAS · Adult female participants with PCOS
1 finding from 1 review

Intervention not reported

Acronyms and grades · Adult female participants with PCOS

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

WDAEb all doses · individuals with normal or abnormal lipid profiles
1 finding from 1 review