Cochrane · systematic review · CD013211

Effect of atorvastatin on testosterone levels

Shawish, MI, Bagheri, B, Musini, VM, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
6
No studies
2
Included studies
NR
No studies 2 · 25%Ungraded 0 · 0%Very low 4 · 50%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings

Population: Male participants
2 questions
OutcomeEffectEvidenceStatus / GRADE
Total testosterone
no estimate extracted2 studies · 140 participantsVery low
Downgraded: risk of bias
Acronyms and grades
no estimate extractedNRNo studies

Summary of findings

Population: Adult female participants with PCOS
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total testosterone
no estimate extracted4 studies · 125 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
FAI
no estimate extracted2 studies · 65 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
SHBG
no estimate extracted2 studies · 65 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Androstenedione
no estimate extracted4 studies · 125 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
DHEAS
no estimate extracted4 studies · 125 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Acronyms and grades
no estimate extractedNRNo studies