Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

38 questions · 38 findings · 3 reviews · Gynaecology and Fertility

No studies found 1 · 2.6%GRADE not reported 0 · 0%Very low 6 · 15.8%Low 20 · 52.6%Moderate 6 · 15.8%High 5 · 13.2%

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

Live birth rate per couple · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether aromatase inhibitors with gonadotropins changes live birth rate per couple compared with anti‐oestrogens with gonadotropins (very low certainty).

1 finding from 1 review

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

Aromatase inhibitors with gonadotropins showed no clear difference in multiple pregnancy rate per couple compared with anti‐oestrogens with gonadotropins (low certainty).

1 finding from 1 review

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

Clinical pregnancy rate · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether aromatase inhibitors with gonadotropins changes clinical pregnancy rate per couple compared with anti‐oestrogens with gonadotropins (very low certainty).

1 finding from 1 review

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

Miscarriage · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether aromatase inhibitors with gonadotropins changes miscarriage rate per couple compared with anti‐oestrogens with gonadotropins (very low certainty).

1 finding from 1 review

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

OHSS · intrauterine insemination (IUI) in women with infertility

Aromatase inhibitors with gonadotropins showed no clear difference in OHSS rate per couple compared with anti‐oestrogens with gonadotropins (low certainty).

1 finding from 1 review

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Live birth rate · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts leads to higher live birth rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

OHSS · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts showed no clear difference in ovarian hyperstimulation syndrome rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review