Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse: OHSS
Letrozole with or without adjuncts showed no clear difference in ovarian hyperstimulation syndrome rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse Ovarian hyperstimulation syndrome rate · infertile women with polycystic ovary syndrome Letrozole with or without adjuncts showed no clear difference in ovarian hyperstimulation syndrome rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty). Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome (2022) · Cochrane Headline outcomes only | no estimate extracted | 10 studies · 1848 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.