Findings

What do systematic reviews say?

9 questions · 9 findings · 2 reviews · Pregnancy and Childbirth · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 3 · 33.3%Very low 4 · 44.4%Low 0 · 0%Moderate 1 · 11.1%High 1 · 11.1%

Amoxicillin vs placebo

Microbiological cure · Pregnant women with a confirmed Chlamydia trachomatis infection

It is very uncertain whether amoxicillin changes microbiological cure compared with placebo (very low certainty).

1 finding from 1 review

Interventions for treating genital Chlamydia trachomatis infection in pregnancy 2017 · Cochrane Headline outcomes only
RR 2 [0.59, 6.79]
1 study · 15 participants
Very low

Amoxicillin vs azithromycin

Microbiological cure · Pregnant women with a confirmed Chlamydia trachomatis infection

It is very uncertain whether amoxicillin changes microbiological cure compared with azithromycin (very low certainty).

1 finding from 1 review

Interventions for treating genital Chlamydia trachomatis infection in pregnancy 2017 · Cochrane Headline outcomes only
RR 0.89 [0.71, 1.12]
2 studies · 144 participants
Very low

Amoxicillin vs erythromycin

Microbiological cure · Pregnant women with a confirmed Chlamydia trachomatis infection

Amoxicillin showed no clear difference in microbiological cure compared with erythromycin (high certainty).

1 finding from 1 review

Interventions for treating genital Chlamydia trachomatis infection in pregnancy 2017 · Cochrane Headline outcomes only
RR 0.97 [0.93, 1.01]
4 studies · 466 participants
High

Amoxicillin vs clindamycin

Microbiological cure · Pregnant women with a confirmed Chlamydia trachomatis infection

Amoxicillin showed no clear difference in microbiological cure compared with clindamycin (moderate certainty).

1 finding from 1 review

Interventions for treating genital Chlamydia trachomatis infection in pregnancy 2017 · Cochrane Headline outcomes only
RR 0.96 [0.89, 1.04]
1 study · 101 participants
Moderate

Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid

Cure of gonococcal infection (microbiological culture) · pregnant women with gonorrhoea infection

It is very uncertain whether intramuscular ceftriaxone changes cure of gonococcal infection (microbiological culture) compared with oral amoxicillin plus oral probenecid (very low certainty).

1 finding from 1 review

Antibiotics for treating gonorrhoea in pregnancy 2018 · Cochrane Headline outcomes only
RR 1.07 [0.98, 1.16]
1 study · 168 participants
Very low

Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid

Incidence of obstetric complications · pregnant women with gonorrhoea infection

1 finding from 1 review

Antibiotics for treating gonorrhoea in pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 168 participants
GRADE not reported

Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid

Incidence of disseminated gonococcal infection · pregnant women with gonorrhoea infection

1 finding from 1 review

Antibiotics for treating gonorrhoea in pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 168 participants
GRADE not reported

Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid

Neonatorum ophthalmia · pregnant women with gonorrhoea infection

1 finding from 1 review

Antibiotics for treating gonorrhoea in pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 168 participants
GRADE not reported

Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid

Adverse events including treatment‐related adverse events · pregnant women with gonorrhoea infection

It is very uncertain whether intramuscular ceftriaxone changes adverse events including treatment‐related adverse events compared with oral amoxicillin plus oral probenecid (very low certainty).

1 finding from 1 review

Antibiotics for treating gonorrhoea in pregnancy 2018 · Cochrane Headline outcomes only
RR 0.33 [0.01, 8.07]
1 study · 168 participants
Very low