Leaving the study early · patients with the treatment of cocaine dependence
Amantadine showed no clear difference in dropouts compared with placebo (moderate certainty).
1 finding from 1 review
Risk for at least one adverse event per patient · patients with the treatment of cocaine dependence
Amantadine showed no clear difference in adverse events as N of participants with at least one adverse event compared with placebo (moderate certainty).
1 finding from 1 review
Abstinence · patients with the treatment of cocaine dependence
Amantadine showed no clear difference in abstinence (objective) N of subjects abstinent at the end of the study compared with placebo (low certainty).
2 findings from 1 review
Activity limitations ‐ not measured · people with postpolio syndrome
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · people with postpolio syndrome
1 finding from 1 review
Reduction in fatigue · people with fatigue in Guillain‐Barré syndrome
Amantadine showed no clear difference in reduction in fatigue of at least 1‐point on the Fatigue Severity… compared with placebo (low certainty).
1 finding from 1 review
OR 0.56 [0.22, 1.35]
74 participants
Low
Fatigue · people with fatigue in Guillain‐Barré syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in activity limitations · people with fatigue in Guillain‐Barré syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participation · people with fatigue in Guillain‐Barré syndrome
1 finding from 1 review
no estimate extracted
74 participants
Low
Health related quality of life after 12 or more weeks or more after commencement of intervention (not reported) · people with fatigue in Guillain‐Barré syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · people with fatigue in Guillain‐Barré syndrome
1 finding from 1 review
no estimate extracted
80 participants
GRADE not reported
Aggression · adults with antisocial personality disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Reconviction · adults with antisocial personality disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Global state/functioning · adults with antisocial personality disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Social functioning · adults with antisocial personality disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · adults with antisocial personality disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Completion of treatment: clonidine versus clonidine plus amantadine, inpatient setting · management of opium withdrawal
It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus clonidine plus amantadine,… compared with other pharmacological detoxification treatment (very low certainty).
1 finding from 1 review
RR 1.03 [0.86, 1.24]
69 participants
Very low
Withdrawal symptoms · management of opium withdrawal
1 finding from 1 review
no estimate extracted
60 participants
Very low
Intervention not reported
Cases of influenza A during prophylaxis ( · children with no influenza A infection (prevention) or with influenza A infection (treatment)
The intervention may leads to lower cases of influenza A during prophylaxis ( (low certainty).
1 finding from 1 review
Intervention not reported
Dizziness ( · children with no influenza A infection (prevention) or with influenza A infection (treatment)
It is very uncertain whether the intervention changes dizziness ( (very low certainty).
1 finding from 1 review