Findings

What do systematic reviews say?

66 questions · 66 findings · 11 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 22 · 33.3%GRADE not reported 6 · 9.1%Very low 21 · 31.8%Low 11 · 16.7%Moderate 6 · 9.1%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- De‐escalation vs standard care · Verbally aggressive behaviour (validated scale) Measured by: Cohen‐Mansfield Agitation Inventory ‐ Verbally Aggressive Behaviour Scale (3 items rated on 7‐point scale, ranging from 1 (never occurs) to 7 (occurs several times an hour); lower score ...
  De‐escalation techniques for managing non‐psychosis induced aggression in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 306 participants
  Very low
Direct match · question page
- De‐escalation vs standard care · Physically aggressive behaviour (validated scale) Measured by: Cohen‐Mansfield Agitation Inventory ‐ Physically Aggressive Behaviour Scale (9 items rated on 7‐point scale, ranging from 1 (never occurs) to 7 (occurs several times an hour); lower sc...
  De‐escalation techniques for managing non‐psychosis induced aggression in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 306 participants
  Very low
Direct match · question page
- Comparison: cannabinoids vs placebo · Agitated or aggressive behaviours in dementia patients, measured on the Cohen‐Mansfield Agitation Inventory (CMAI) Scale (range 29 to 203, with 29 meaning no symptoms, and higher number of points indicating more severe symptoms)Â
  Cannabinoids for the treatment of dementia 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 100 participants
  Low
Direct match · question page
- Aggressive vs conservative blood transfusion · Mortality
  Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 230 participants
  GRADE not reported
Direct match · question page
- Structured risk assessment vs standard professional care · Scientific behaviour: aggression – clinically important change in aggressive/violent behaviour, as defined by the individual studies
  Risk assessment for aggressive behaviour in schizophrenia 2024 · Cochrane Headline outcomes only
  RR 0.59 [0.41, 0.85]
  1 study · 1852 participants
  Moderate

Aggressive vs conservative blood transfusion

All‐cause mortality · people with SCD

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 230 participants
GRADE not reported

Aggressive vs conservative blood transfusion

Serious complications related to SCD ‐ cholecystectomy ACS · people with SCD

It is very uncertain whether aggressive changes serious complications related to SCD ‐ cholecystectomy ACS compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 0.84 [0.38, 1.84]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Serious complications related to SCD ‐ cholecystectomy painful crisis · people with SCD

It is very uncertain whether aggressive changes serious complications related to SCD ‐ cholecystectomy painful crisis compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 0.3 [0.09, 1.04]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Serious infection ‐ cholecystectomy · people with SCD

It is very uncertain whether aggressive changes serious infection ‐ cholecystectomy compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 1.75 [0.59, 5.18]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Perioperative complications ‐ cholecystectomy complications (any) · people with SCD

It is very uncertain whether aggressive changes perioperative complications ‐ cholecystectomy complications (any) compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 0.75 [0.36, 1.55]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Transfusion‐related complications ‐ cholecystectomy complications (any) · people with SCD

It is very uncertain whether aggressive changes transfusion‐related complications ‐ cholecystectomy complications… compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 1.85 [0.89, 3.88]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Quality of life · people with SCD

The review found no eligible studies for this question.

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Structured risk assessment vs usual care

Behaviour: aggressive or violent behaviour · aggressive behaviour in schizophrenia

Structured risk assessment probably leads to lower scientific behaviour: aggression – clinically important change in… compared with standard professional care (moderate certainty).

1 finding from 1 review

Risk assessment for aggressive behaviour in schizophrenia 2024 · Cochrane Headline outcomes only
RR 0.59 [0.41, 0.85]
1 study · 1852 participants
Moderate

Summary of findings table ‐ Anger management vs waiting list control

Aggressive behaviour: severity of incidents: Aberrant Behaviour Checklist (ABC – irritability subscale – key worker report – post‐treatment (Analysis 1.2.1) · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 158 participants
Moderate

Summary of findings table ‐ Meditation based on mindfulness vs treatment

Physical aggression · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Aggressive behaviour: aggressive events – carer reports – post‐training (Analysis 4.1) · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 128 participants
Low

Summary of findings table ‐ Positive behavioural support vs treatment

Aggressive behaviour: Aberrant Behaviour Checklist (ABC) Total – at 6 months (Analysis 2.1.1) · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 275 participants
Moderate

Cannabinoids vs placebo

Agitated or aggressive behaviours in dementia patients, measured on the Cohen‐Mansfield Agitation Inventory (CMAI) Scale (range 29 to 203, with 29 meaning no symptoms, and higher number of points indicating more severe symptoms)Â · diagnosis of dementia (dementia in Alzheimer’s disease, vascular dementia, or mixed dementia; any severity

1 finding from 1 review

Cannabinoids for the treatment of dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 100 participants
Low

Phenytoin (antiepileptic) vs placebo

Aggression · adults with antisocial personality disorder

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

SOCIAL SKILLS vs no intervention

Teacher‐rated general behaviour Measured by: Self‐Control Rating Scale; Conners Behavior Rating Scale: Aggressiveness Index; Disruptive Behavior Disorders Rating Scale; Conners Teacher Rating Scale: Conduct Problems Index; Strengths and Difficulti... · Children and adolescents with ADHD

1 finding from 1 review

Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years 2019 · Cochrane Headline outcomes only
no estimate extracted
1002 participants
Low

SOCIAL SKILLS vs no intervention

Parent‐rated general behaviour Measured by: Strengths and Difficulties Questionnaire (parent‐rated; total scores); Conners Behavior Rating Scale: Aggressiveness Index; Disruptive Behavior Disorders Rating Scale; Behavior Rating Inventory of Execut... · Children and adolescents with ADHD

1 finding from 1 review

Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years 2019 · Cochrane Headline outcomes only
no estimate extracted
995 participants
Very low

De‐escalation vs usual care

Physically aggressive behaviour (validated scale) Measured by: Cohen‐Mansfield Agitation Inventory ‐ Physically Aggressive Behaviour Scale (9 items rated on 7‐point scale, ranging from 1 (never occurs) to 7 (occurs several times an hour); lower sc... · people with dementia

1 finding from 1 review

De‐escalation techniques for managing non‐psychosis induced aggression in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 306 participants
Very low

De‐escalation vs usual care

Verbally aggressive behaviour (validated scale) Measured by: Cohen‐Mansfield Agitation Inventory ‐ Verbally Aggressive Behaviour Scale (3 items rated on 7‐point scale, ranging from 1 (never occurs) to 7 (occurs several times an hour); lower score ... · people with dementia

1 finding from 1 review

De‐escalation techniques for managing non‐psychosis induced aggression in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 306 participants
Very low

CHLORPROMAZINE vs metiapine

Behaviour: aggressive or violent behaviour · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Chlorpromazine versus metiapine for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Structured risk assessment vs usual care

Use of coercive measure: use of seclusion room (time, days) · aggressive behaviour in schizophrenia

Structured risk assessment showed no clear difference in use of coercive measure: use of seclusion room (time, days) compared with standard professional care (low certainty).

1 finding from 1 review

Risk assessment for aggressive behaviour in schizophrenia 2024 · Cochrane Headline outcomes only
RR 0.92 [0.27, 3.07]
1 study · 20 participants
Low