Cochrane · systematic review · CD011655
Chlorpromazine versus metiapine for schizophrenia
Zare, M, Bazrafshan, A · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 71.4%Ungraded 0 · 0%Very low 2 · 28.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Chlorpromazine versus metiapine for schizophrenia
Population: people with schizophrenia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global state: clinically important improvement Clinical Global Impression Chlorpromazine vs metiapine | RR 1.11 [0.84, 1.47] | 2 studies · 120 participants | Very low Downgraded: risk of bias, imprecision |
Mental state: clinically important improvement Chlorpromazine vs metiapine | no estimate extracted | NR | No studies |
Adverse effects. Specific: movement disorders ‐ parkinsonism Chlorpromazine vs metiapine | RR 0.97 [0.46, 2.03] | 2 studies · 70 participants | Very low Downgraded: risk of bias, imprecision |
Service use: readmission due to relapse Chlorpromazine vs metiapine | no estimate extracted | NR | No studies |
Satisfaction of participant or care provider with treatment Chlorpromazine vs metiapine | no estimate extracted | NR | No studies |
Behaviour: aggressive or violent behaviour Chlorpromazine vs metiapine | no estimate extracted | NR | No studies |
Cost of care Chlorpromazine vs metiapine | no estimate extracted | NR | No studies |