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What do systematic reviews say?

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Evidence found and GRADE certainty

174 questions · 184 findings · 13 reviews · Pain, Palliative and Supportive Care

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No studies found 61 · 33.2%GRADE not reported 23 · 12.5%Very low 57 · 31%Low 33 · 17.9%Moderate 10 · 5.4%High 0 · 0%

Intervention not reported

Percentage of participants not requiring postoperative opioids over initial 72 hours · adults aged ≥ 18 years undergoing elective surgery at any surgical site

The review found no eligible studies for this question.

1 finding from 1 review

Ibuprofen vs paracetamol

Serious adverse events, defined as any medical event at any dose that results in death, is life‐threatening, requires hospitalisation (or prolongation of existing hospitalisation) or results in permanent damage or disability (FDA 2016) · children with acute postoperative pain

The review found no eligible studies for this question.

1 finding from 1 review

Ibuprofen vs morphine

Serious adverse events, defined as any medical event at any dose that results in death, is life‐threatening, requires hospitalisation (or prolongation of existing hospitalisation) or results in permanent damage or disability (FDA 2016) · children with acute postoperative pain

The review found no eligible studies for this question.

1 finding from 1 review

Ibuprofen vs ketorolac

Serious adverse events, defined as any medical event at any dose that results in death, is life‐threatening, requires hospitalisation (or prolongation of existing hospitalisation) or results in permanent damage or disability (FDA 2016) · children with acute postoperative pain

The review found no eligible studies for this question.

1 finding from 1 review

Ibuprofen vs placebo

Serious adverse events, defined as any medical event at any dose that results in death, is life‐threatening, requires hospitalisation (or prolongation of existing hospitalisation) or results in permanent damage or disability (FDA 2016) · children with acute postoperative pain

The review found no eligible studies for this question.

1 finding from 1 review