Question · asked by 1 review
Summary of findings: liposomal bupivacaine vs bupivacaine: Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale)
- Population
- aged 18 years and older undergoing elective surgery at any surgical site
- Intervention
- Summary of findings: liposomal bupivacaine
- Comparison
- bupivacaine
- Outcome
- Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale)
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: liposomal bupivacaine vs bupivacaine hydrochloride Mean pain score at 12, 24, 48, 72 and 96 hours following surgery (NRS 0 to 10) · aged 18 years and older undergoing elective surgery at any surgical site Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain (2017) · Cochrane Headline outcomes only | no estimate extracted | 1 study · 134 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Summary of findings: liposomal bupivacaine vs placebo · aged 18 years and older undergoing elective surgery at any surgical site · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.