Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

82 questions · 82 findings · 9 reviews · ENT

No studies found 23 · 28%GRADE not reported 0 · 0%Very low 40 · 48.8%Low 12 · 14.6%Moderate 7 · 8.5%High 0 · 0%

Adenoidectomy and unilateral ventilation tube vs unilateral ventilation tube only

Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether adenoidectomy and unilateral ventilation tube changes presence or persistence of OME (3 years ‐ long‐term) № of… compared with unilateral ventilation tube only (very low certainty).

1 finding from 1 review

Adenoidectomy and ventilation tubes vs watchful waiting

Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether adenoidectomy and ventilation tubes changes presence/persistence of OME (at 2 years ‐ long‐term) № of… compared with no treatment/watchful waiting (very low certainty).

1 finding from 1 review

Adenoidectomy (with or without myringotomy) vs watchful waiting

Specific adverse events: haemorrhage · children aged 6 months to 12 years with otitis media with effusion (OME)

Adenoidectomy (with or without myringotomy) probably leads to higher adverse event: haemorrhage № of participants: 480(1 RCT) compared with no treatment/watchful waiting (moderate certainty).

1 finding from 1 review

Adenoidectomy and bilateral ventilation tubes vs bilateral ventilation tubes only

Specific adverse events: haemorrhage · children aged 6 months to 12 years with otitis media with effusion (OME)

Adenoidectomy and bilateral ventilation tubes showed no clear difference in adverse event: haemorrhage № of participants: 791(2 RCTs) compared with bilateral ventilation tubes only (low certainty).

1 finding from 1 review

Ventilation tubes vs no treatment

Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether ventilation tubes changes hearing ‐ return to normal hearing Randomised by ear: normal defined… compared with no treatment (very low certainty).

1 finding from 1 review

Ventilation tubes vs myringotomy

Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether ventilation tubes changes hearing ‐ return to normal *Ventilation tubes versus laser… compared with myringotomy (very low certainty).

1 finding from 1 review