Poor oral health-related quality of life (OHRQoL) · children
Age 5 years was associated with higher odds of poor OHRQoL than age older than 5 years.
1 finding from 1 review
OR 3.68 [2.20, 5.17]
1 study
GRADE not reported
Caries experience (mean DMFT) · Adults aged 19-60 years
Studies of older adults (mean age >33.4 years) had higher pooled DMFT than younger adults, but the age to DMFT meta-regression was not statistically significant; ungraded observational evidence.
5 findings from 1 review
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Gingivitis · School children aged 3-12 years in Sharjah clinic
Children aged 6 years or younger had lower odds of gingivitis.
1 finding from 1 review
Poor oral health-related quality of life (OHRQoL) · Children aged 3-12 years
Children aged 3 years had higher odds of poor OHRQoL than older children (OR 2.00, 95% CI 1.42-2.57; 2 studies; ungraded).
2 findings from 1 review
OR 2.00 [1.42, 2.57]
2 studies
GRADE not reported
OR 2.13 [1.50, 2.76]
2 studies
GRADE not reported
Spontaneous space closure · Children and adolescents with maxillary permanent first molar extraction
In the maxilla, age 8-10 years was not associated with a statistically significant difference in space closure odds.
1 finding from 1 review
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Fluoride varnish applied before 4 years of age may leads to higher fluorosis (percentage prevalence in permanent teeth) compared with no fluoride varnish application (low certainty).
1 finding from 1 review
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Fluoride varnish applied before 4 years of age (biannual) showed no clear difference in fluorosis (percentage prevalence in permanent teeth) compared with placebo varnish (low certainty).
1 finding from 1 review
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, extraction before age 8 (vs after 10) increases odds of space closure (OR 5.01; low certainty).
1 finding from 1 review
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, extraction at age 8-10 (vs after 10) increases odds of space closure (OR 3.32; low certainty).
1 finding from 1 review
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, extraction at 11-12 vs 8-10 years showed no significant difference in one analysis (OR 0.82; not GRADE-rated).
2 findings from 1 review
Caries (DMFT/DMFS) in mixed/permanent dentition · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
Higher early Streptococcus mutans colonization is associated with more caries in the mixed/permanent dentition (2 studies; not pooled; not GRADE-rated).
1 finding from 1 review
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
It is very uncertain whether started toothbrushing with fluoride toothpaste before 4 years… changes fluorosis (percentage prevalence in permanent teeth) compared with started after 4 years (later start) (very low certainty).
1 finding from 1 review
Dental caries · Adult participants in 25 meta-regression studies
The unadjusted meta-regression coefficient for older mean age was 4.324884.
2 findings from 1 review
Oral health-related quality of life · Adolescents (10-19 years)
The abstract reports older age is associated with worse OHRQoL, but the body notes the evidence on age is limited and conflicting (narrative synthesis; no pooled estimate or GRADE rating).
2 findings from 1 review
Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomesCommunity/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
Worse oral health status, older age, female sex and worse socioeconomic status were significantly associated with worse OHRQoL. [Body: the influence of religion and age on OHRQoL is unknown; Biological data such as…
Studies not reported
GRADE not reported
no estimate extracted
Studies not reported
GRADE not reported
Dental caries · School children aged 11-17 years in Sharjah
Older age was associated with higher DMFT.
1 finding from 1 review
Early childhood caries (ECC) · Healthy children under 6 years of age (6 months to 6 years); preschool children
In the primary pooled analysis, late tooth brushing initiation was associated with a non-significant 40% higher odds of early childhood caries (OR 1.40, 95% CI 0.91 to 2.16), with very high heterogeneity (I2=90.5%); ungraded.
2 findings from 1 review
Oral health-related quality of life · Adolescents (10-19 years)
The umbrella review reported insufficient scientific evidence to support an association between dental agenesis and oral health-related quality of life.
2 findings from 1 review
Early childhood caries (ECC) · Children aged 0-5 years in North Africa
Age 48-59 months was associated with higher odds of ECC (OR 2.602).
2 findings from 1 review
OR 2.602 [1.122, 2.302]
1 study
GRADE not reported
OR 2.845 [1.128, 2.072]
1 study
GRADE not reported
Poor oral health-related quality of life (OHRQoL) · Children aged 3-12 years
Lower maternal education was associated with poor OHRQoL (OR 1.12, 95% CI 1.00-1.23; 4 studies; high heterogeneity; CI lower bound at the null; ungraded).
1 finding from 1 review
OR 1.12 [1.00, 1.23]
4 studies
GRADE not reported
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
For resin-based bonding agents, fluoride release did not significantly change WSL initiation (RR 0.97); subgroup not separately GRADE-rated.
1 finding from 1 review