Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

137 questions · 158 findings · 21 reviews · Oral Health

No studies found 49 · 31%GRADE not reported 73 · 46.2%Very low 19 · 12%Low 9 · 5.7%Moderate 8 · 5.1%High 0 · 0%

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Duration of orthodontic treatment, number of visits during active treatment (scheduled and unscheduled) and duration of visits · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Costs: direct cost of treatment · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Adverse effects of treatment · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
1 finding from 1 review

Ultrasonic instrumentation used alone (any ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal) vs Hand instrumentation used alone (files and reamers used manually)

Outcome not reported · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of internal resorption,…

The review found no eligible studies for this question.

1 finding from 1 review

Hand instrumentation in conjunction with (as an adjunct to) an ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal vs Hand instrumentation used alone (files and reamers used manually)

Outcome not reported · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of internal resorption,…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Treatment time · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Length of hospital stay · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Cost of oral care · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Amount of analgesia · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Incidence of systemic infection · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Relief of dysphagia · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Relief of pain · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Patient quality of life · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Periodontal treatment: scaling and root planing (SRP) plus advice vs Community care: advice only

Serum high-sensitivity C-reactive protein (hs-CRP) · Patients with cardiovascular disease and chronic periodontitis
1 finding from 1 review

Bio-active restorative materials vs Any conventional restorative material

Treatment failure (planned; no eligible studies) · Children with carious primary teeth after vital or non-vital pulp therapy

No eligible studies were found evaluating bio-active restorative materials for restoring carious primary teeth after pulp therapy.

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Bleeding, as measured by: amount of blood loss; complete cessation of bleeding as assessed clinically by the investigator; time required for the control of bleeding · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Discomfort associated with the procedure · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Adverse events · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Active self-ligating brackets vs Passive self-ligating brackets

Time to alignment · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Active self-ligating brackets showed no clear difference in time to alignment (days) compared with passive self-ligating brackets; GRADE not reported.

1 finding from 1 review

Active self-ligating brackets vs Passive self-ligating brackets

Amount of crowding (upper anterior crowding) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
1 finding from 1 review
  • Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
    baseline
    Only baseline upper anterior crowding reported (Pandis 2010a, n=70); evidence of baseline imbalance between groups (P=0.04); no post-treatment between-group crowding estimate reported.
    1 study
    GRADE not reported