Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

46 questions · 46 findings · 13 reviews · Eyes and Vision · Headline outcomes only

No studies found 10 · 21.7%GRADE not reported 3 · 6.5%Very low 8 · 17.4%Low 18 · 39.1%Moderate 7 · 15.2%High 0 · 0%

PACK‐CXL with standard therapy vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Proportion of participants with reduction in intraocular inflammation at 4 to 8 weeks Assessed by corneal keratic precipitates, anterior chamber cellular reaction, or other appropriate measure · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review

Combined surgery vs phacoemulsification alone

Proportion using one or more medications at one year after surgery Number of participants · patients with eyes with cataract and glaucoma

Combined surgery may leads to lower proportion using one or more medications at one year after surgery… compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Combined surgery vs phacoemulsification alone

Need for additional surgery: proportion of participants who received additional surgery to control IOP at 1 year · patients with eyes with cataract and glaucoma

Combined surgery showed no clear difference in proportion who received re‐operation to control IOP within one year… compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Combined surgery vs phacoemulsification alone

Proportion who received intervention for surgical complications within one year Number of participants · patients with eyes with cataract and glaucoma

Combined surgery showed no clear difference in proportion who received intervention for surgical complications… compared with phacoemulsification alone (low certainty).

1 finding from 1 review