Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 24 findings · 5 reviews · Eyes and Vision · Headline outcomes only

No studies found 2 · 8.3%GRADE not reported 0 · 0%Very low 11 · 45.8%Low 6 · 25%Moderate 5 · 20.8%High 0 · 0%

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Anatomic success, defined as patency to lacrimal irrigation · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in anatomic success, defined as patency to lacrimal irrigation compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Functional success, defined as the relief of epiphora · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in functional success, defined as the relief of epiphora compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Ostium size on nasal endoscopy · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in ostium size on nasal endoscopy compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Intervention not reported

Treatment success (at 6 months) · children with congenital nasolacrimal duct obstruction (NLDO)
1 finding from 1 review

Intervention not reported

Treatment success (at other time points) · children with congenital nasolacrimal duct obstruction (NLDO)

It is very uncertain whether the intervention changes treatment success (at other time points) (very low certainty).

1 finding from 1 review

Intervention not reported

Proportion of participants requiring secondary procedures · children with congenital nasolacrimal duct obstruction (NLDO)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Cost‐effectiveness · children with congenital nasolacrimal duct obstruction (NLDO)
1 finding from 1 review