Findings

What do systematic reviews say?

7 questions · 9 findings · 4 reviews · Dental caries

Sort:Best matchNewest Highest certainty Download CSV

No studies found 3 · 33.3%GRADE not reported 1 · 11.1%Very low 2 · 22.2%Low 3 · 33.3%Moderate 0 · 0%High 0 · 0%

Fluoride toothpaste vs Placebo (non-fluoride) toothpaste or fluoride toothpaste of a different concentration

Adverse effects of toothpaste · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
Closest to 36 months
16 studies assessed possible side effects, principally oral (soft tissue) pathologies and tooth staining. 6 studies reported no untoward events; 6 reported greater staining in the stannous fluoride group; 1 reported no…
16 studies
GRADE not reported

A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique

Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of anterior teeth, irrespective of…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the restorative care of amelogenesis imperfecta in children and adolescents 2013 · Cochrane All outcomes
Main results: No studies met the inclusion criteria for this review. Effects of interventions: No studies met the inclusion criteria.
0 studies
No studies found

A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique

Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of posterior teeth, irrespective of…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the restorative care of amelogenesis imperfecta in children and adolescents 2013 · Cochrane All outcomes
Main results: No studies met the inclusion criteria for this review. Effects of interventions: No studies met the inclusion criteria.
0 studies
No studies found

Initiation of water fluoridation (artificial or natural) vs Low/non-fluoridated water (0.4 ppm fluoride or less)

Disparities in caries across socioeconomic status (SES) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years

1 finding from 1 review

Water fluoridation for the prevention of dental caries 2015 · Cochrane All outcomes
There is insufficient information to determine whether initiation of a water fluoridation programme results in a change in disparities in caries levels across SES. Data from 3 observational studies (participants not…
3 studies · 35399 participants
Low

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Disparities in caries across socioeconomic status (SES) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review

Water fluoridation for the prevention of dental caries 2015 · Cochrane All outcomes
No evidence to determine the effect of the cessation of water fluoridation on disparities in caries across SES.
0 studies
No studies found

Interdental brushing plus toothbrushing vs Flossing plus toothbrushing

Gingivitis · Adults, 16 years and older (dentate)

Interdental brushing plus toothbrushing may leads to lower gingivitis (bleeding and gingival indices; standardised across… compared with flossing plus toothbrushing (low certainty).

2 findings from 1 review · compare the 2 reviews

Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults 2013 · Cochrane All outcomes
1 month (4 to 6 weeks)
SMD -0.53 [-0.81, -0.24]
7 studies · 326 participants
Low
Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults 2013 · Cochrane All outcomes
3 months (12 weeks)
SMD -1.98 [-5.42, 1.47]
2 studies · 107 participants
Very low

Interdental brushing plus toothbrushing vs Flossing plus toothbrushing

Plaque · Adults, 16 years and older (dentate)

Interdental brushing plus toothbrushing showed no clear difference in plaque (plaque indices; standardised across indices) compared with flossing plus toothbrushing (low certainty).

2 findings from 1 review · compare the 2 reviews

Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults 2013 · Cochrane All outcomes
1 month (4 to 6 weeks)
SMD 0.10 [-0.13, 0.33]
7 studies · 326 participants
Low
Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults 2013 · Cochrane All outcomes
3 months (12 weeks)
SMD -2.14 [-5.25, 0.97]
2 studies · 107 participants
Very low