Intervention not reported
Total CRBSI (confirmed and suspected) Clinical and microbiological assessments · newborn infants who require a central venous catheter
The intervention leads to lower total CRBSI (confirmed and suspected) Clinical and microbiological… (high certainty).
1 finding from 1 review
Intervention not reported
Mortality Clinical assessment · newborn infants who require a central venous catheter
It is very uncertain whether the intervention changes mortality Clinical assessment (very low certainty).
1 finding from 1 review
Intervention not reported
Number of infants with hypoglycaemia Blood sugar level: glucose meter or laboratory‐based plasma glucose level · newborn infants who require a central venous catheter
The intervention leads to lower number of infants with hypoglycaemia Blood sugar level: glucose… (high certainty).
1 finding from 1 review
Intervention not reported
Incidence of pulmonary tuberculosis in children with HIV infection ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under
The intervention showed no clear difference in incidence of pulmonary tuberculosis in children with HIV infection ‐… (moderate certainty).
1 finding from 1 review
Intervention not reported
Mean FEV1 % predicted ‐ azithromycin prophylaxis only · children with cystic fibrosis aged 12 years and under
1 finding from 1 review
Intervention not reported
Mean FEV1 % predicted ‐ ciprofloxacin prophylaxis only · children with cystic fibrosis aged 12 years and under
1 finding from 1 review
Intervention not reported
Episodes of pulmonary exacerbations ‐ azithromycin prophylaxis only · children with cystic fibrosis aged 12 years and under
The intervention leads to lower episodes of pulmonary exacerbations ‐ azithromycin prophylaxis only (high certainty).
1 finding from 1 review
Intervention not reported
Incidence of Pneumocystis carinii pneumonia infection in children with cancer ‐ trimethoprim‐sulfamethoxazole prophylaxis only · children with cancers aged 12 years and under
The intervention probably leads to lower incidence of Pneumocystis carinii pneumonia infection in children… (moderate certainty).
1 finding from 1 review
Intervention not reported
Mortality in children with HIV infection ‐ overall · children with HIV infection aged 12 years and under
The intervention showed no clear difference in mortality in children with HIV infection ‐ overall (moderate certainty).
1 finding from 1 review
Intervention not reported
Mortality in children with HIV infection ‐ co‐trimoxazole prophylaxis only · children with HIV infection aged 12 years and under
The intervention probably leads to lower mortality in children with HIV infection ‐ co‐trimoxazole… (moderate certainty).
1 finding from 1 review
Intervention not reported
Mortality in children with HIV infection ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under
The intervention showed no clear difference in mortality in children with HIV infection ‐ isoniazid prophylaxis only (low certainty).
1 finding from 1 review
Intervention not reported
Incidence of adverse events ‐ overall · children with HIV infection aged 12 years and under
The intervention showed no clear difference in incidence of adverse events ‐ overall (moderate certainty).
1 finding from 1 review
Intervention not reported
Incidence of adverse events ‐ co‐trimoxazole prophylaxis only · children with HIV infection aged 12 years and under
The intervention showed no clear difference in incidence of adverse events ‐ co‐trimoxazole prophylaxis only (moderate certainty).
1 finding from 1 review
Intervention not reported
Incidence of adverse events ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under
The intervention showed no clear difference in incidence of adverse events ‐ isoniazid prophylaxis only (moderate certainty).
1 finding from 1 review
Intervention not reported
Incidence of Pseudomonas infection in children with cystic fibrosis ‐ ciprofloxacin prophylaxis only · children with cystic fibrosis aged 12 years and under
The intervention showed no clear difference in incidence of Pseudomonas infection in children with cystic fibrosis… (moderate certainty).
1 finding from 1 review
Intervention not reported
Mean FEV1 % predicted · children with cystic fibrosis aged 12 years and under
1 finding from 1 review
All‐cause mortality—same beta lactam Survival · patients with sepsis
Monotherapy showed no clear difference in all‐cause mortality—same beta lactam Survival compared with combination therapy compared (low certainty).
1 finding from 1 review
All‐cause mortality—different beta lactam · patients with sepsis
Monotherapy showed no clear difference in all‐cause mortality—different beta lactam compared with combination therapy compared (low certainty).
1 finding from 1 review
Fever clearance time · children with acute pyelonephritis
1 finding from 1 review
Increase in serum creatinine during treatment · children with acute pyelonephritis
Different dosing regimens of aminoglycosides (daily showed no clear difference in increase in serum creatinine during treatment compared with 8 hourly) (low certainty).
1 finding from 1 review