DMFS (decayed, missing, filled surfaces) increment, occlusal surfaces · Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars
Pit and fissure sealant and fluoride varnish showed no statistically significant difference in DMFS increment at 24 months (SMD -0.13, 95% CI -0.67 to 0.40; I2=92%; not GRADE-rated).
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
Chlorhexidine (CHX) led to lower reduction in level of contamination by particles >5 um (droplets) at… compared with essential oils/herbal mouthwash; GRADE not reported.
4 findings from 1 review
MD -44.1 [-59.12, -29.08]
1 study · 20 participants
GRADE not reported
Bay 1993 compared 0.12% CHX with essential oil mouthwash C (Listerine) at pharynx level (Andersen's level 2), which was considered patient level and hence was not analysed. No pooled estimate or GRADE rating.
1 study
GRADE not reported
MD -12.21 [-15.58, -8.83]
3 studies · 76 participants
Low
Show 1 more finding
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether povidone iodine changes reduction in level of contamination by particles >5 um (droplets) at… compared with ozonated water (very low certainty).
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty).
9 findings from 1 review
MD 8.8 [2.7, 14.9]
1 study · 20 participants
Very low
MD 17.4 [11.3, 23.5]
1 study · 20 participants
Very low
MD -11.5 [-18.37, -4.63]
1 study · 20 participants
Very low
Show 6 more findings
MD -8.8 [-14.9, -2.7]
1 study · 20 participants
Very low
MD -2.2 [-9.07, 4.67]
1 study · 20 participants
Very low
MD -30 [-85.86, 25.86]
1 study · 30 participants
Very low
MD -0.2 [-6.3, 5.9]
1 study · 20 participants
Very low
MD 13.6 [6.73, 20.47]
1 study · 20 participants
Very low
MD 4.43 [-2.27, 11.13]
2 studies · 50 participants
Very low
Adverse events · Children with caries-free second primary molars, aged 4-8 years (dental clinic, Turkey and Spain)
The review found no eligible studies for this question.
1 finding from 1 review
Mineral loss (transversal microradiography) · Enamel/dentin specimens with initial caries lesions (or sound surfaces) in intraoral (in situ) appliances worn by patients
Under remineralizing conditions, nHA produced significantly more remineralization than the negative control (MD 350, 95% CI 179 to 521; very low certainty).
2 findings from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
5 findings from 1 review
At operator level, because of high heterogeneity (I2 = 98%), the results were not meta-analysed (6 studies, 196 participants). No pooled estimate or GRADE rating.
6 studies · 196 participants
GRADE not reported
MD -632.94 [-1267.33, 1.45]
3 studies · 80 participants
Very low
MD -101.1 [-107.01, -95.19]
1 study · 20 participants
Low
Show 2 more findings
Bay 1993 compared 0.12% CHX with distilled water (30-second rinse) and evaluated the outcome at patient level (Andersen's level 2, oropharynx); the data were not included in the meta-analysis. No pooled estimate or…
1 study
GRADE not reported
At assistant level, because of high heterogeneity (I2 = 96%), the results were not meta-analysed (4 studies, 136 participants). No pooled estimate or GRADE rating.
4 studies · 136 participants
GRADE not reported
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether cetylpyridinium chloride (CPC) changes reduction in level of contamination by particles >5 um (droplets) at… compared with no rinsing (very low certainty).
3 findings from 1 review
MD -0.75 [-1.32, -0.18]
2 studies · 200 participants
Very low
MD -34.8 [-65.92, -3.68]
1 study · 30 participants
Very low
MD -583 [-958.36, -207.64]
1 study · 30 participants
Low
Progression of non-cavitated enamel caries · 'Healthy' children with caries-free second primary molars, aged 3-5 years (schools and kindergartens, India and China)
The review found no eligible studies for this question.
1 finding from 1 review
Development of >=1 new carious lesion (caries incidence) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department, dental hospital, France)
2 findings from 1 review
Reduction in level of contamination by particles <=5 um (droplet nuclei) at >=2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles <=5 um (droplet… compared with povidone iodine (very low certainty).
2 findings from 1 review
Alpha diversity (Chao1, Observed, Shannon) · Adults providing oral (saliva/supragingival plaque) 16S rRNA microbiome samples
In adults, caries-vs-health alpha diversity differed for the Shannon index but not Chao1/Observed (ungraded).
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether tempered cetylpyridinium chloride changes reduction in level of contamination by particles >5 um (droplets) at… compared with cold cetylpyridinium chloride (very low certainty).
2 findings from 1 review
Development of >=1 new carious lesion (caries incidence) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric clinic/dental school,…
Glass ionomer-based sealant may leads to lower development of >=1 new carious lesion (caries incidence) compared with no sealant (low certainty).
2 findings from 1 review
Oral care vs No oral care
Outcome not reported · Residents of nursing homes and other long-term care facilities
The review found no eligible studies for this question.
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether boric acid changes reduction in level of contamination by particles >5 um (droplets) at… compared with water (very low certainty).
2 findings from 1 review
MD -29.3 [-32.65, -25.95]
1 study · 60 participants
Very low
MD -14.04 [-16.47, -11.61]
1 study · 60 participants
Very low
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with ozonated water (very low certainty).
1 finding from 1 review
Mean caries increment (mean number of new cavitated occlusal lesions) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department, dental hospital, France)
1 finding from 1 review
All CVD-related death · Patients with cardiovascular disease and chronic periodontitis
The review found no eligible studies for this question.
1 finding from 1 review