Pain, assessed using the CRIES pain scale, ranging from 0 to 10, during the procedure— opioids versus facilitated tucking · procedural pain in neonates
1 finding from 1 review
Any harms ‐ severe apnea requiring resuscitation · procedural pain in neonates
It is very uncertain whether opioids changes any harms ‐ severe apnea requiring resuscitation compared with no treatment/placebo (very low certainty).
1 finding from 1 review
Episodes of bradycardia · procedural pain in neonates
It is very uncertain whether opioids changes episodes of bradycardia compared with no treatment/placebo (very low certainty).
1 finding from 1 review
Episodes of apnea · procedural pain in neonates
Opioids may leads to higher episodes of apnea compared with no treatment/placebo (low certainty).
1 finding from 1 review
Hypotension · procedural pain in neonates
1 finding from 1 review
Outcome№ of participants(studies) · children with acute postoperative pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Relief of pain · children with acute postoperative pain
2 findings from 1 review
no estimate extracted
50 participants
GRADE not reported
no estimate extracted
50 participants
GRADE not reported
Reduction in pain intensity · children with acute postoperative pain
2 findings from 1 review
no estimate extracted
0 participants
GRADE not reported
no estimate extracted
2 participants
GRADE not reported
Nausea and vomiting · children with acute postoperative pain
It is very uncertain whether diclofenac changes nausea, vomiting, or both during study period № of participants:… compared with placebo (very low certainty).
1 finding from 1 review
Any bleeding during study period № of participants: 100(2 RCTs)d · children with acute postoperative pain
It is very uncertain whether diclofenac changes any bleeding during study period № of participants: 100(2 RCTs)d compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events during the study period · children with acute postoperative pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Changes in mean participant‐reported ocular pain from baseline to 24 hours · corneal abrasion (post‐trauma or post‐surgical)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants with complications at longest time point Up to 1 week · corneal abrasion (post‐surgical)
1 finding from 1 review
Changes in mean participant‐reported ocular pain from baseline to 48 hours · corneal abrasion (post‐trauma or post‐surgical)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Changes in mean participant‐reported ocular pain from baseline to 72 hours · corneal abrasion (post‐trauma or post‐surgical)
1 finding from 1 review
Proportion of participants without complete resolution of epithelial defects by 24 to 72 hours · corneal abrasion (post‐trauma or post‐surgical)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants with complications at longest time point Up to 2 weeks · corneal abrasion (post‐trauma or post‐surgical)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Changes in mean participant‐reported ocular pain from baseline to 24 hours · corneal abrasion (post‐surgical)
1 finding from 1 review
Changes in mean participant‐reported ocular pain from baseline to 48 hours · corneal abrasion (post‐surgical)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Changes in mean participant‐reported ocular pain from baseline to 72 hours · corneal abrasion (post‐surgical)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found