What do systematic reviews say?

Intervention not reported

• Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a network… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 1469 participants
  GRADE not reported

Intervention not reported

• Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a network… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Intervention not reported

• Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a network… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

1-19 remaining teeth vs 20-32 remaining teeth

In prospective cohorts, adults with 1-19 teeth had a higher cumulative incidence of ACVD-related events than adults with 20-32 teeth (RR 1.69, 95% CI 1.13 to 2.53; 2 cohort studies, I2=60%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

• Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of Survival… 2021 All outcomes

  Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report
  RR 1.69 [1.13, 2.53]
  2 studies · 165066 participants
  High

Edentulous (0 remaining teeth) vs 20-32 remaining teeth

In prospective cohorts, edentulous adults (0 teeth) had a higher cumulative incidence of all-cause mortality than adults with 20-32 teeth (RR 2.27, 95% CI 1.82 to 2.83; 8 cohort studies, I2=94%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

• Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of Survival… 2021 All outcomes

  Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report
  RR 2.27 [1.82, 2.83]
  8 studies · 180222 participants
  High

0-10 remaining teeth vs 25-32 remaining teeth

In prospective cohorts, adults with 0-10 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 2.65, 95% CI 1.84 to 3.81; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

• Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of Survival… 2021 All outcomes

  Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report
  RR 2.65 [1.84, 3.81]
  4 studies · 193546 participants
  High

Repeated single embryo transfer (mixed policies) vs multiple embryo transfer

Repeated single embryo transfer (mixed policies) showed no clear difference in cumulative live birth compared with multiple embryo transfer (low certainty).

• Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
  RR 0.95 [0.82, 1.1]
  4 studies · 985 participants
  Low

Repeated single embryo transfer (mixed policies) vs multiple embryo transfer

Repeated single embryo transfer (mixed policies) probably leads to lower multiple pregnancy compared with multiple embryo transfer (moderate certainty).

• Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
  odds ratio 0.13 [0.08, 0.21]
  4 studies · 985 participants
  Moderate

Repeated single embryo transfer (mixed policies) vs multiple embryo transfer

Repeated single embryo transfer (mixed policies) showed no clear difference in clinical pregnancy rate compared with multiple embryo transfer (low certainty).

• Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
  RR 0.95 [0.84, 1.08]
  3 studies · 943 participants
  Low

Repeated single embryo transfer (mixed policies) vs multiple embryo transfer

Repeated single embryo transfer (mixed policies) showed no clear difference in miscarriage rate compared with multiple embryo transfer (low certainty).

• Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
  odds ratio 2.14 [0.93, 4.95]
  2 studies · 282 participants
  Low

Single vs multiple embryo transfer

Single may leads to lower live birth compared with multiple embryo transfer (low certainty).

• Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
  RR 0.67 [0.59, 0.75]
  12 studies · 1904 participants
  Low

Single vs multiple embryo transfer

Single probably leads to lower multiple pregnancy compared with multiple embryo transfer (moderate certainty).

• Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
  odds ratio 0.16 [0.12, 0.22]
  13 studies · 1952 participants
  Moderate

Single vs multiple embryo transfer

Single may leads to lower clinical pregnancy compared with multiple embryo transfer (low certainty).

• Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
  RR 0.7 [0.64, 0.77]
  10 studies · 1860 participants
  Low

Single vs multiple embryo transfer

Single showed no clear difference in miscarriage rate compared with multiple embryo transfer (low certainty).

• Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
  odds ratio 0.96 [0.66, 1.42]
  7 studies · 1560 participants
  Low

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 77 participants
  Moderate

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 77 participants
  Moderate

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

The review found no eligible studies for this question.

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

The review found no eligible studies for this question.

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

The review found no eligible studies for this question.

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention probably leads to lower presence of PDA on third to fourth day of life (after 72 hours of… (moderate certainty).

• Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants 2020 · Cochrane Headline outcomes only
  RR 0.39 [0.31, 0.48]
  9 studies · 1029 participants
  Moderate