Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,661 questions · 2,751 findings · 453 reviews

No studies found 593 · 21.6%GRADE not reported 277 · 10.1%Very low 538 · 19.6%Low 712 · 25.9%Moderate 516 · 18.8%High 115 · 4.2%

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious maternal morbidity or death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious maternal morbidity or death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

GnRH antagonist vs long‐course GnRH agonist

Cycle cancellation due to poor ovarian response · women undergoing assisted reproductive technology (ART)

GnRH antagonist probably leads to higher cycle cancellation due to poor ovarian response compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Self‐monitoring or self‐management of oral anticoagulation vs usual care

Thromboembolic events · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

Self‐monitoring or self‐management of oral anticoagulation probably leads to lower thromboembolic events compared with standard care (moderate certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

All‐cause mortality · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation probably leads to lower all‐cause mortality compared with standard care (moderate certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

Major bleeding · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation showed no clear difference in major haemorrhage compared with standard care (low certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

Minor haemorrhage · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation showed no clear difference in minor haemorrhage compared with standard care (low certainty).

1 finding from 1 review

Self‐monitoring or self‐management of oral anticoagulation vs usual care

All‐cause mortality · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

Self‐monitoring or self‐management of oral anticoagulation showed no clear difference in all‐cause mortality compared with standard care (moderate certainty).

1 finding from 1 review