Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,411 questions · 2,571 findings · 265 reviews

No studies found 543 · 21.1%GRADE not reported 169 · 6.6%Very low 676 · 26.3%Low 731 · 28.4%Moderate 399 · 15.5%High 53 · 2.1%

Music‐based therapeutic interventions vs usual care or other activities

Mood disturbance or negative affect: depression · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Mood disturbance or negative affect: anxiety · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Behavioural problems: agitation or aggression · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Behavioural problems: overall · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Social behaviour: music vs other activities · people with dementia (all resided in institutional settings)
2 findings from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: episodes of re‐bleeding over 10 days All treatments (topical and oral) · adults with nasal haemorrhage (epistaxis)

Tranexamic acid probably leads to lower control of epistaxis: episodes of re‐bleeding over 10 days All… compared with placebo plus usual care or usual care alone (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: episodes of re‐bleeding over 10 days Oral treatment only · adults with nasal haemorrhage (epistaxis)

Tranexamic acid probably leads to lower control of epistaxis: episodes of re‐bleeding over 10 days Oral… compared with placebo plus usual care or usual care alone (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: episodes of re‐bleeding over 10 days Topical application (10% gel) only · adults with nasal haemorrhage (epistaxis)

Tranexamic acid showed no clear difference in control of epistaxis: episodes of re‐bleeding over 10 days Topical… compared with placebo plus usual care or usual care alone (low certainty).

1 finding from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: time to stop initial bleeding (proportion of patients whose bleeding is controlled in ≤ 30 minutes) · adults with nasal haemorrhage (epistaxis)

Tranexamic acid showed no clear difference in control of epistaxis: time to stop initial bleeding (proportion of… compared with placebo plus usual care or usual care alone (low certainty).

1 finding from 1 review

Tranexamic acid vs placebo + standard care

Severity of re‐bleeding: proportion of patients requiring blood transfusion within 10 days · adults with nasal haemorrhage (epistaxis)

Tranexamic acid showed no clear difference in severity of re‐bleeding: proportion of patients requiring blood… compared with placebo plus usual care or usual care alone (low certainty).

1 finding from 1 review