Question · asked by 1 review
Tranexamic acid vs placebo + standard care: Control of epistaxis: time to stop initial bleeding (proportion of patients whose bleeding is controlled in ≤ 30 minutes)
- Population
- adults with nasal haemorrhage (epistaxis)
- Intervention
- Tranexamic acid
- Comparison
- placebo + standard care
- Outcome
- Control of epistaxis: time to stop initial bleeding (proportion of patients whose bleeding is controlled in ≤ 30 minutes)
Tranexamic acid showed no clear difference in control of epistaxis: time to stop initial bleeding (proportion of… compared with placebo plus usual care or usual care alone (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Tranexamic acid vs placebo plus usual care or usual care alone Control of epistaxis: time to stop initial bleeding (proportion of patients whose bleeding is controlled in ≤ 30 minutes) · adults with nasal haemorrhage (epistaxis) Tranexamic acid showed no clear difference in control of epistaxis: time to stop initial bleeding (proportion of… compared with placebo plus usual care or usual care alone (low certainty). Tranexamic acid for patients with nasal haemorrhage (epistaxis) (2018) · Cochrane Headline outcomes only | RR 0.79 [0.56, 1.11] | 1 study · 68 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Tranexamic acid for patients with nasal haemorrhage (epistaxis) 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.