Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,720 questions · 15,377 findings · 900 reviews

No studies found 3,865 · 25.1%GRADE not reported 2,291 · 14.9%Very low 3,875 · 25.2%Low 3,287 · 21.4%Moderate 1,681 · 10.9%High 378 · 2.5%

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Clobetasol propionate cream vs prednisone

Adverse events: severe complications at day 21 · bullous pemphigoid

Clobetasol propionate cream may leads to lower adverse events: severe complications at day 21 compared with oral prednisone (low certainty).

1 finding from 1 review

Mild clobetasol propionate cream regimen (10 to 30 g/day) vs standard clobetasol propionate cream regimen (40 g/day)

Disease control (healing of skin lesions) at day 21 · bullous pemphigoid

Mild clobetasol propionate cream regimen (10 to 30 g/day) showed no clear difference in disease control (healing of skin lesions) at day 21.… compared with standard clobetasol propionate cream regimen (40 g/day) (moderate certainty).

1 finding from 1 review

Mild clobetasol propionate cream regimen (10 to 30 g/day) vs standard clobetasol propionate cream regimen (40 g/day)

Adverse events at 1 year · bullous pemphigoid

Mild clobetasol propionate cream regimen (10 to 30 g/day) showed no clear difference in adverse events at 1 year compared with standard clobetasol propionate cream regimen (40 g/day) (low certainty).

1 finding from 1 review

Doxycycline vs prednisolone

Disease control · bullous pemphigoid

Doxycycline leads to lower disease control at 6 weeks (unadjusted raw data) compared with prednisolone (high certainty).

1 finding from 1 review

An intervention in which one's attention is on the experience of stress (feelings, thoughts, behavior) vs no intervention/wait list/placebo/no stress‐reduction intervention

Stress symptoms ( · healthcare workers
3 findings from 1 review

An intervention in which one's attention is away from the experience of stress vs no intervention/wait list/placebo/no stress‐reduction intervention

Stress symptoms ( · healthcare workers
3 findings from 1 review

An intervention in which the focus is on work‐related risk factors on an individual level vs no intervention/no stress‐reduction interventionfor stress reduction

Stress symptoms ( · healthcare workers
3 findings from 1 review

Summary of findings table ‐ Anger management vs waiting list control

Aggressive behaviour: severity of incidents: Aberrant Behaviour Checklist (ABC – irritability subscale – key worker report – post‐treatment (Analysis 1.2.1) · outwardly aggressive behaviour in people with intellectual disability
1 finding from 1 review

Summary of findings table ‐ Positive behavioural support vs treatment

Mental state: Common Mental Disorder (CMD) – at 6 months (Analysis 2.2.1) (CMD) · outwardly aggressive behaviour in people with intellectual disability

Summary of findings table ‐ Positive behavioural support showed no clear difference in mental state: Common Mental Disorder (CMD) – at 6 months (Analysis… compared with treatment (low certainty).

1 finding from 1 review