Mild clobetasol propionate cream regimen (10 to 30 g/day) vs standard clobetasol propionate cream regimen (40 g/day): Disease control (healing of skin lesions) at day 21
- Population
- bullous pemphigoid
- Intervention
- Mild clobetasol propionate cream regimen (10 to 30 g/day)
- Comparison
- standard clobetasol propionate cream regimen (40 g/day)
- Outcome
- Disease control (healing of skin lesions) at day 21
Mild clobetasol propionate cream regimen (10 to 30 g/day) showed no clear difference in disease control (healing of skin lesions) at day 21.… compared with standard clobetasol propionate cream regimen (40 g/day) (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Mild clobetasol propionate cream regimen (10 to 30 g/day) vs standard clobetasol propionate cream regimen (40 g/day) Disease control (healing of skin lesions) at day 21. Intention‐to‐treat analysis, all participants · bullous pemphigoid Mild clobetasol propionate cream regimen (10 to 30 g/day) showed no clear difference in disease control (healing of skin lesions) at day 21.… compared with standard clobetasol propionate cream regimen (40 g/day) (moderate certainty). Interventions for bullous pemphigoid (2023) · Cochrane Headline outcomes only | RR 1 [0.97, 1.03] | 1 study · 312 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for bullous pemphigoid 2023 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.