Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Supine midline head position vs any other supine head position

Intraventricular haemorrhage, Papile grade 3/4 · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes intraventricular haemorrhage, grade 3 to 4 compared with any other supine head position (very low certainty).

1 finding from 1 review

Intervention not reported

Death from pericarditis · HIV‐negative people with tuberculous pericarditis

The intervention probably leads to lower death from pericarditis (moderate certainty).

1 finding from 1 review

Intervention not reported

Constrictive pericarditis · HIV‐negative people with tuberculous pericarditis

It is very uncertain whether the intervention changes constrictive pericarditis (very low certainty).

1 finding from 1 review

Intervention not reported

Repeat pericardiocentesis · HIV‐negative people with tuberculous pericarditis

The intervention showed no clear difference in repeat pericardiocentesis (low certainty).

1 finding from 1 review

Intervention not reported

Death from pericarditis · HIV‐positive people with tuberculous pericarditis. Most patients (80%) not on antiretroviral drugs

It is very uncertain whether the intervention changes death from pericarditis (very low certainty).

1 finding from 1 review

Intervention not reported

Constrictive pericarditis · HIV‐positive people with tuberculous pericarditis. Most patients (80%) not on antiretroviral drugs

The intervention showed no clear difference in constrictive pericarditis (low certainty).

1 finding from 1 review

Intervention not reported

Repeat pericardiocentesis · HIV‐positive people with tuberculous pericarditis. Most patients (80%) not on antiretroviral drugs

The intervention showed no clear difference in repeat pericardiocentesis (low certainty).

1 finding from 1 review

Eradication therapy combined with periodontal therapy vs eradication therapy alone

Eradication rate of gastric H. pylori · patients with gastric Helicobacter pylori infection

Eradication therapy combined with periodontal therapy probably leads to higher eradication rate of gastric H. pylori compared with eradication therapy alone (moderate certainty).

1 finding from 1 review

Eradication therapy combined with periodontal therapy vs eradication therapy alone

Non‐recurrence rate of gastric H. pylori · patients with gastric Helicobacter pylori infection

Eradication therapy combined with periodontal therapy may leads to higher non‐recurrence rate of gastric H. pylori compared with eradication therapy alone (low certainty).

1 finding from 1 review

Rutosides vs placebo

Complications associated with varicose veins and leg oedema (deep vein thrombosis) · Pregnant women with varicose veins and leg oedema in pregnancy

Rutoside showed no clear difference in complications associated with varicose veins and leg oedema (deep… compared with placebo (moderate certainty).

1 finding from 1 review

Rutosides vs placebo

Symptoms associated with varicose veins and oedema (improvement in symptoms) · Pregnant women with varicose veins and leg oedema in pregnancy

Rutoside probably leads to higher symptoms associated with varicose veins and oedema (improvement in… compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Failure rate of post‐pyloric placement of the enteral feeding tube assessed by abdominal radiograph Radiographic assessment of successful tube placement · patients needing post‐pyloric placement of naso‐enteral feeding tubes

It is very uncertain whether the intervention changes failure rate of post‐pyloric placement of the enteral feeding tube… (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes control of bleeding Success in control the active variceal bleeding compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review