Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

411 questions · 420 findings · 42 reviews

No studies found 99 · 23.6%GRADE not reported 35 · 8.3%Very low 135 · 32.1%Low 114 · 27.1%Moderate 34 · 8.1%High 3 · 0.7%

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Clinical cure · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs may leads to higher clinical cure rate (short‐term) compared with conventional antifungal drugs (low certainty).

2 findings from 1 review

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Mycological cure · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs may leads to higher mycological cure rate (short‐term) compared with conventional antifungal drugs (low certainty).

2 findings from 1 review

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Relapse · non‐pregnant women with vulvovaginal candidiasis

It is very uncertain whether probiotics used as adjuvants to conventional antifungal drugs changes relapse rate compared with conventional antifungal drugs (very low certainty).

1 finding from 1 review

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Rate of serious adverse events · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs showed no clear difference in rate of serious adverse events compared with conventional antifungal drugs (low certainty).

1 finding from 1 review

Antibiotics plus probiotics vs placebo or no intervention

Failure to induce clinical remission at end of study · people with active UC

It is very uncertain whether antibiotics plus probiotics changes failure to induce clinical remission at end of study compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Intervention not reported

Incidence of AAD: Probiotic dose (≥5 billion CFUs of probiotics/day) · Children receiving antibiotic treatment between 4 and 28 days duration for a variety of infections

The intervention probably leads to lower incidence of AAD: Probiotic dose (≥5 billion CFUs of probiotics/day) (moderate certainty).

1 finding from 1 review

Intervention not reported

Symptomatic bacterial UTI in adults and children in patients with and without recurrent UTI Probiotics versus placebo ( · adults and children at risk of UTI

The intervention showed no clear difference in symptomatic bacterial UTI in adults and children in patients with… (low certainty).

1 finding from 1 review

Intervention not reported

Symptomatic bacterial UTI in adults and children with recurrent UTI Probiotics versus placebo ( · adults and children at risk of UTI

The intervention showed no clear difference in symptomatic bacterial UTI in adults and children with recurrent UTI… (low certainty).

1 finding from 1 review

Intervention not reported

Symptomatic bacterial UTI in women with recent UTI Probiotics versus antibiotics ( · adults and children at risk of UTI

The intervention showed no clear difference in symptomatic bacterial UTI in women with recent UTI Probiotics versus… (low certainty).

1 finding from 1 review