Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

538 questions · 568 findings · 96 reviews

No studies found 106 · 18.7%GRADE not reported 39 · 6.9%Very low 160 · 28.2%Low 151 · 26.6%Moderate 92 · 16.2%High 20 · 3.5%

Pharmacological interventions vs placebo

acceptability ‐ drop‐outs due to adverse events: post‐intervention · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to adverse events: post‐intervention compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Acceptability · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: post‐intervention compared with placebo (very low certainty).

2 findings from 1 review

Pharmacological interventions vs placebo

Incidence of depression ‐ post‐intervention: 0 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ post‐intervention: 0 months compared with placebo (very low certainty).

1 finding from 1 review

A physical activity programme (weight‐bearing) vs no physical activity

Time spent walking (minutes per week, activity monitor) · people with NMD
3 findings from 1 review

Physical activity vs usual care

Overall survival (time interval between enrolment in the study and death of the person from any cause) · adults with non‐advanced colorectal cancer treated surgically or with neoadjuvant or adjuvant therapy, or both

The review found no eligible studies for this question.

1 finding from 1 review

Remote and web 2.0 vs control

Physical activity · patients with promoting physical activity

Remote and web 2.0 probably leads to higher dichotomous outcomes: 12 months Self‐reported physical activity… compared with control (moderate certainty).

3 findings from 1 review