Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,268 questions · 1,343 findings · 197 reviews

No studies found 317 · 23.6%GRADE not reported 189 · 14.1%Very low 356 · 26.5%Low 271 · 20.2%Moderate 173 · 12.9%High 37 · 2.8%

Zuclopenthixol dihydrochloride vs OTHER ANTIPSYCHOTIC: h. THIOTHIXENE

Global state: Average endpoint global state score (clinically improved) (CGI ‐ unchanged/worse) · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes global state: Average endpoint global state score (clinically… compared with thiothixene (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride vs chlorpromazine

Adverse effects: Clinically important general adverse effect (EPSEs) · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect (EPSEs) compared with chlorpromazine (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride vs placebo

Clinically significant response on global state · patients with schizophrenia

It is very uncertain whether ZUCLOPENTHIXOL DIHYDROCHLORIDE changes clinically significant response on global state ‐ as defined by each… compared with PLACEBO (very low certainty).

1 finding from 1 review