Zuclopenthixol dihydrochloride vs OTHER ANTIPSYCHOTIC: h. THIOTHIXENE: Global state: Average endpoint global state score (clinically improved) (CGI ‐ unchanged/worse)
It is very uncertain whether zuclopenthixol dihydrochloride changes global state: Average endpoint global state score (clinically… compared with thiothixene (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Zuclopenthixol dihydrochloride vs thiothixene Global state: Average endpoint global state score (clinically improved) (unchanged/worse ‐ CGI) · schizophrenia It is very uncertain whether zuclopenthixol dihydrochloride changes global state: Average endpoint global state score (clinically… compared with thiothixene (very low certainty). Zuclopenthixol dihydrochloride for schizophrenia (2017) · Cochrane Headline outcomes only | RR 0.5 [0.17, 1.46] | 1 study · 20 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.