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Evidence found and GRADE certainty

1,085 questions · 1,232 findings · 66 reviews · All outcomes

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No studies found 218 · 17.7%GRADE not reported 745 · 60.5%Very low 179 · 14.5%Low 65 · 5.3%Moderate 25 · 2%High 0 · 0%

Antiretroviral therapy (any, including cART) vs No antiretroviral medication (treatment-naive)

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

ART was associated with lower oral candidiasis prevalence.

1 finding from 1 review

Occlusal intervention as an adjunct to periodontal therapy vs Sham (placebo) occlusal intervention as an adjunct to periodontal therapy

Outcome not reported · Adults (aged 18 years or older) with a clinical diagnosis of (chronic) periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Adverse effects (e.g. thermal sensitivity, over-eruption, TMJ symptoms, poor aesthetics, reduced oral hygiene) · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Attachment change · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Change in probing pocket depth (PPD) · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to surgical periodontal therapy showed no clear difference in probing (pocket) depth change (difference in mean reduction, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy vs conventional therapy

Healing of MRONJ · People with established (manifest) MRONJ

It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty).

1 finding from 1 review

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Change in probing pocket depth (PPD) · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to non-surgical periodontal therapy showed no clear difference in probing (pocket) depth change (difference in mean reduction, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Adverse effects (e.g. thermal sensitivity, over-eruption, TMJ symptoms, poor aesthetics, reduced oral hygiene) · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Attachment change · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to non-surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

One type of occlusal intervention as an adjunct to periodontal therapy vs A different type of occlusal intervention as an adjunct to periodontal therapy (head-to-head)

Outcome not reported · Adults (aged 18 years or older) with a clinical diagnosis of (chronic) periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Recurrence · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Total mortality · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)

PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in total mortality compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).

1 finding from 1 review

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)

PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in locoregional recurrence compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).

1 finding from 1 review

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review