Findings

What do systematic reviews say?

343 questions · 347 findings · 29 reviews · Eyes and Vision

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No studies found 94 · 27.1%GRADE not reported 11 · 3.2%Very low 81 · 23.3%Low 110 · 31.7%Moderate 47 · 13.5%High 4 · 1.2%

Topical mydriatics vs depot delivery systems

AE: participant‐reported ocular discomfort—week 1 · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical mydriatics vs depot delivery systems

AE: participant‐reported ocular discomfort—month 1 · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical mydriatics vs depot delivery systems

AE: vitreous loss—any time point during or after surgery · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intracameral mydriatics vs depot delivery systems

Mean pupillary diameter—at the time the surgeon performs capsulorhexis (mm) · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical mydriatics vs intracameral mydriatics

Mean pupillary diameter—at the beginning of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 242 participants
Low

Intracameral mydriatics vs depot delivery systems

Mean pupillary diameter—at the beginning of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Intracameral mydriatics vs depot delivery systems

Mean pupillary diameter—at the end of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Intracameral mydriatics vs depot delivery systems

Intraoperative surgical time—total intraoperative time (min) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Intracameral mydriatics vs depot delivery systems

AE: participant‐reported ocular discomfort—week 1 · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intracameral mydriatics vs depot delivery systems

AE: participant‐reported ocular discomfort—month 1 · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intracameral mydriatics vs depot delivery systems

Adverse events · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical mydriatics vs intracameral mydriatics

Mean pupillary diameter—at the end of cataract surgery (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 799 participants
Low

Topical mydriatics vs intracameral mydriatics

Intraoperative surgical time—total intraoperative time (min) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 817 participants
Low

Topical mydriatics vs intracameral mydriatics

Total time it took for the surgeon to perform phacoemulsification (seconds) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 48 participants
Very low

Topical mydriatics vs intracameral mydriatics

AE: participant‐reported ocular discomfort—week 1 · patients undergoing cataract surgery

It is very uncertain whether topical mydriatics changes AE: participant‐reported ocular discomfort—week 1 compared with intracameral mydriatics (very low certainty).

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 10.57 [1.37, 81.34]
1 study · 555 participants
Very low

Topical mydriatics vs intracameral mydriatics

AE: participant‐reported ocular discomfort—month 1 · patients undergoing cataract surgery

Topical mydriatics probably leads to higher AE: participant‐reported ocular discomfort—month 1 compared with intracameral mydriatics (moderate certainty).

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 2.51 [1.36, 4.65]
1 study · 543 participants
Moderate

Topical mydriatics vs intracameral mydriatics

AE: posterior capsule rupture · patients undergoing cataract surgery

Topical mydriatics showed no clear difference in AE: posterior capsule rupture compared with intracameral mydriatics (low certainty).

2 findings from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low
Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Visual acuity · infantile nystagmus syndrome

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in head posture ‐ not reported · infantile nystagmus syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in intensity of the nystagmus waveform · infantile nystagmus syndrome

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low