Asthma clinical scores · children hospitalised with an acute asthma exacerbation
Combination of anticholinergics + beta2‐agonists showed no clear difference in asthma clinical scores compared with beta2‐agonists alone (moderate certainty).
1 finding from 1 review
Incidence of admissions to the ICU · children hospitalised with an acute asthma exacerbation
1 finding from 1 review
Overall withdrawals · children hospitalised with an acute asthma exacerbation
Combination of anticholinergics + beta2‐agonists showed no clear difference in overall withdrawals compared with beta2‐agonists alone (moderate certainty).
1 finding from 1 review
Adverse health events · children hospitalised with an acute asthma exacerbation
1 finding from 1 review
Intervention not reported
PPI versus placebo Symptomatic outcome measures · patients with heartburn remission in gastro‐oesophageal reflux disease‐like symptoms
The intervention leads to lower PPI versus placebo Symptomatic outcome measures (high certainty).
1 finding from 1 review
Intervention not reported
H2RA versus placebo · patients with heartburn remission in gastro‐oesophageal reflux disease‐like symptoms
The intervention probably leads to lower H2RA versus placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Prokinetic versus placebo · patients with heartburn remission in gastro‐oesophageal reflux disease‐like symptoms
1 finding from 1 review
Intervention not reported
PPI versus H2RA · patients with heartburn remission in gastro‐oesophageal reflux disease‐like symptoms
The intervention probably leads to lower PPI versus H2RA (moderate certainty).
1 finding from 1 review
Intervention not reported
PPI versus prokinetic · patients with heartburn remission in gastro‐oesophageal reflux disease‐like symptoms
The intervention may leads to lower PPI versus prokinetic (low certainty).
1 finding from 1 review
Intervention not reported
PPI versus placebo · patients with heartburn remission in endoscopy negative reflux disease
The intervention probably leads to lower PPI versus placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
H2RA versus placebo · patients with heartburn remission in endoscopy negative reflux disease
The intervention probably leads to lower H2RA versus placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
PPI versus H2RA · patients with heartburn remission in endoscopy negative reflux disease
The intervention may leads to lower PPI versus H2RA (low certainty).
1 finding from 1 review
Intervention not reported
PPI versus prokinetic · patients with heartburn remission in endoscopy negative reflux disease
The intervention may leads to lower PPI versus prokinetic (low certainty).
1 finding from 1 review
Intervention not reported
Treatment failure at 1 month or less · patients with acute otitis media
The intervention led to higher treatment failure at 1 month or less; GRADE not reported.
1 finding from 1 review
Intervention not reported
Treatment failure at 8 to 19 days · patients with acute otitis media
The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.
1 finding from 1 review
Intervention not reported
Treatment failure at 20 to 30 days · patients with acute otitis media
The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.
1 finding from 1 review
Intervention not reported
Treatment failure at 8 to 19 days · patients with acute otitis media
The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.
1 finding from 1 review
Intervention not reported
Treatment failure at 20 to 30 days · patients with acute otitis media
The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.
1 finding from 1 review
Intervention not reported
Treatment failure at 3 months or less · patients with acute otitis media
The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.
1 finding from 1 review
Intervention not reported
Treatment failure at 90 days · patients with acute otitis media
The intervention showed no clear difference in treatment failure at 90 days; GRADE not reported.
1 finding from 1 review