What do systematic reviews say?

Summary of Findings Table ‐ PBI?APBI vs WBRT

Summary of Findings Table ‐ PBI?APBI showed no clear difference in distant metastasis‐free survival (DM‐FS) compared with WBRT (moderate certainty).

• Partial breast irradiation versus whole breast radiotherapy for early breast cancer 2021 · Cochrane Headline outcomes only
  HR 0.95 [0.8, 1.13]
  7 studies · 11033 participants
  Moderate

Summary of Findings Table ‐ PBI?APBI vs WBRT

Summary of Findings Table ‐ PBI?APBI showed no clear difference in subsequent mastectomy compared with WBRT (high certainty).

• Partial breast irradiation versus whole breast radiotherapy for early breast cancer 2021 · Cochrane Headline outcomes only
  OR 0.98 [0.78, 1.23]
  3 studies · 3740 participants
  High

Surgery for Bell's palsy vs medical treatment (oral prednisolone) or no treatment

It is very uncertain whether surgery for Bell's palsy changes complete recovery of facial nerve function at 12 months Defined as:… compared with medical treatment (oral prednisolone) or no treatment (very low certainty).

• Surgical interventions for the early management of Bell's palsy 2021 · Cochrane Headline outcomes only
  RR 0.76
  2 studies · 57 participants
  Very low

Surgery for Bell's palsy vs medical treatment (oral prednisolone) or no treatment

It is very uncertain whether surgery for Bell's palsy changes side effects and complications of treatmentMeasured by clinical… compared with medical treatment (oral prednisolone) or no treatment (very low certainty).

• Surgical interventions for the early management of Bell's palsy 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 57 participants
  Very low

Paracetamol (single administration, any dose) vs placebo

Paracetamol (single administration, any dose) may leads to higher adequate pain relief as reported by women compared with placebo (low certainty).

• Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
  RR 2.14 [1.59, 2.89]
  10 studies · 1279 participants
  Low

Paracetamol (single administration, any dose) vs placebo

Paracetamol (single administration, any dose) may leads to lower additional pain relief compared with placebo (low certainty).

• Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
  RR 0.34 [0.21, 0.55]
  8 studies · 1132 participants
  Low

Paracetamol (single administration, any dose) vs placebo

Paracetamol (single administration, any dose) showed no clear difference in maternal drug adverse effects (nausea) compared with placebo (low certainty).

• Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
  RR 0.18 [0.01, 3.66]
  1 study · 232 participants
  Low

Paracetamol (single administration, any dose) vs placebo

Paracetamol (single administration, any dose) showed no clear difference in maternal drug adverse effects (sleepiness) compared with placebo (low certainty).

• Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
  RR 0.89 [0.18, 4.3]
  1 study · 232 participants
  Low

Paracetamol (single administration, any dose) vs placebo

The review found no eligible studies for this question.

• Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Bethanechol vs placebo

The review found no eligible studies for this question.

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Suprapubic catheterisation vs intermittent self‐catheterisation

The review found no eligible studies for this question.

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Suprapubic catheterisation vs intermittent self‐catheterisation

It is very uncertain whether suprapubic catheterisation changes adverse events (acute complication after surgery) compared with intermittent self‐catheterisation (very low certainty).

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  RR 0.77 [0.24, 2.49]
  1 study · 71 participants
  Very low

Suprapubic catheterisation vs intermittent self‐catheterisation

The review found no eligible studies for this question.

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Suprapubic catheterisation vs intermittent self‐catheterisation

It is very uncertain whether suprapubic catheterisation changes urinary tract infections in the first month after surgery compared with intermittent self‐catheterisation (very low certainty).

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  RR 0.77 [0.53, 1.13]
  2 studies · 95 participants
  Very low

Suprapubic catheterisation vs intermittent self‐catheterisation

The review found no eligible studies for this question.

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Bethanechol vs placebo

The review found no eligible studies for this question.

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Bethanechol vs placebo

The review found no eligible studies for this question.

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Bethanechol vs placebo

The review found no eligible studies for this question.

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Bethanechol vs placebo

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 39 participants
  Very low

Bethanechol vs placebo

The review found no eligible studies for this question.

• Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found