Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,355 questions · 2,459 findings · 279 reviews

No studies found 556 · 22.6%GRADE not reported 490 · 19.9%Very low 593 · 24.1%Low 479 · 19.5%Moderate 243 · 9.9%High 98 · 4%

Supported employment vs other vocational approaches

Employment ‐ obtained any job during the study (high=better) · adults with severe mental illness

It is very uncertain whether supported employment changes employment ‐ obtained any job during the study (high=better) compared with other vocational approaches (very low certainty).

1 finding from 1 review

RDP with I-bar clasps / mesial rests vs RDP with circumferential clasps / distal rests

Change in abutment tooth mobility at 60 months · Partially edentulous patients treated with a removable dental prosthesis (RDP)

RDP with I-bar clasps / mesial rests showed no clear difference in change in abutment tooth mobility at 60 months compared with RDP with circumferential clasps / distal rests; GRADE not reported.

1 finding from 1 review

Xenogeneic collagen matrix (porcine; Mucograft) vs Connective tissue autograft (palate)

Keratinised mucosa height change · Patients with implant-supported prostheses and <=1 mm keratinised mucosa

Xenogeneic collagen matrix (porcine; Mucograft) showed no clear difference in keratinised mucosa height change compared with connective tissue autograft (palate); GRADE not reported.

1 finding from 1 review

Xenogeneic collagen matrix (porcine; Mucograft) vs Connective tissue autograft (palate)

Recession (aesthetics) · Patients with implant-supported prostheses and <=1 mm keratinised mucosa

Xenogeneic collagen matrix (porcine; Mucograft) showed no clear difference in recession (aesthetics) compared with connective tissue autograft (palate); GRADE not reported.

1 finding from 1 review

RDP with I-bar clasps / mesial rests vs RDP with circumferential clasps / distal rests

Treatment success rate · Partially edentulous patients treated with a removable dental prosthesis (RDP)

RDP with I-bar clasps / mesial rests showed no clear difference in treatment success (5-year) compared with RDP with circumferential clasps / distal rests; GRADE not reported.

1 finding from 1 review

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Complication at augmented site · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in complication at augmented site compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Augmentation procedure failure · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in augmentation procedure failure compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Perimplant bone loss · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in perimplant bone loss (3 years) compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Vertical bone gain · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in vertical bone gain compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

Oral paracetamol vs placebo

At least 50% reduction in pain · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 4 hours (using pain intensity… compared with placebo; GRADE not reported.

3 findings from 1 review