Enamel caries proportion · European adolescents aged 18 years
Pooled enamel caries proportion was 0.29 (I² = 99.3%).
1 finding from 1 review
Enamel caries proportion · European adolescents aged 12–19 years
Enamel caries made up about half of total caries experience (pooled proportion 0.50, 95% CI 0.39 to 0.65; 7 studies; higher in 12–15 than 16–19-year-olds; not GRADE-rated).
3 findings from 1 review
Proportion 0.50 [0.39, 0.65]
7 studies · 7056 participants
GRADE not reported
Proportion 0.37 [0.24, 0.56]
3 studies
GRADE not reported
Proportion 0.56 [0.42, 0.76]
8 studies
GRADE not reported
Progression of non-cavitated enamel caries · Children with caries-free second primary molars, aged 4-8 years (dental clinic, Turkey and Spain)
The review found no eligible studies for this question.
1 finding from 1 review
Gingivitis · School children (aged 4 to 15 years), primary and secondary schools in the UK and India
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark)
The review found no eligible studies for this question.
1 finding from 1 review
Caries experience at the surface level (dmfs/defs) · Children (mean age newborn to ~5.2 years) and their parents/carers
Behaviour change interventions delivered by non-dental health workers produced a small, statistically significant reduction in caries experience at the surface level (dmfs SMD -0.15, 95% CI -0.25 to -0.04; 12 studies); the review judged the overall evidence to be of low quality (not GRADE-rated).
1 finding from 1 review
Retention of sealant (complete or partial retention) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric clinic/dental school,…
1 finding from 1 review
Chadwick 2005: one or more sealants fully/partially retained in 69 (31.2%) children at 12-30 months; Joshi 2019: at 12 months 75 (43.6%) teeth completely retained, 58 (33.7%) partially retained, 39 (22.7%) completely…
2 studies
GRADE not reported
Pain at two weeks (postobturation) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment showed no clear difference in pain at two weeks (postobturation) compared with multiple-visit root canal treatment (two or more visits); GRADE not reported.
1 finding from 1 review
Early childhood caries (ECC) - association at lead SNP rs1044956 (7:24854765; nearest gene(s) OSBPL3, NPVF) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5 cohorts (N=2974)
The common variant rs1044956 near OSBPL3, NPVF showed suggestive (not genome-wide significant) association with ECC (Z = 4.551, p = 5.35e-6); genetic association, ungraded.
2 findings from 1 review
Retention of sealant (complete or partial retention) · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark)
It is very uncertain whether autopolymerised sealant changes retention of sealant (complete or partial retention) compared with light polymerised sealant (very low certainty).
1 finding from 1 review
Retention of sealant (complete or partial retention) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department, dental hospital, France)
1 finding from 1 review
At 12 months, sealants on 96 (70.1%) surfaces completely retained, 25 (18.3%) partially retained, 16 (11.6%) completely lost; at 24 months, 58 (45.3%) completely retained, 29 (22.7%) partially retained, 41 (32%)…
1 study
GRADE not reported
Adverse events · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department, dental hospital, France)
The review found no eligible studies for this question.
1 finding from 1 review
Dental attendance at orthodontist · School children, secondary school in the UK (aged 11 to 13 years)
It is very uncertain whether criteria-based screening with specific (personalised) referral letter changes dental attendance at orthodontist compared with criteria-based screening with non-specific referral letter (very low certainty).
1 finding from 1 review
Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
Reduction in pain intensity · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) may leads to lower pain intensity at follow-up (12 months) compared with usual care, waiting list or no treatment (control) (low certainty).
2 findings from 1 review
Treatment failure (annual failure rate) · Children (aged 5-8 years) with Class-II caries in primary molars, no pulp therapy
Etching dentine for 7 s rather than 15 s lowered bulk-fill composite failure (5.8% vs 16.9% annual failure) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review
Caries lesion initiation/progression (ICDAS score, laser fluorescence/DIAGNOdent, photographic pixels, enamel acid resistance) · Patients (children and adults, age 3-40 years) with initial enamel caries lesions (non-orthodontic and orthodontic)
No meta-analysis was possible for the 5 in vivo RCTs (high heterogeneity); narratively nHA showed generally no significant difference versus fluoridated dentifrice, and the evidence was not graded (ungraded).
1 finding from 1 review
Efficacy of nano-hydroxyapatite on caries prevention-a systematic review and meta-analysis. 2022 All outcomesMedian follow-up 6 months (range 6-12 months) · In vivo (clinical); non-orthodontic and orthodontic patients
No meta-analysis was performed for the in vivo studies owing to high heterogeneity (population, control group, outcomes, follow-up periods, risk of bias) and differing statistical designs (e.g., non-inferiority);…
5 studies · 420 participants
GRADE not reported
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Hypnosis showed no clear difference in pain intensity compared with relaxation; GRADE not reported.
1 finding from 1 review
Not pooled (clinical heterogeneity). Abrahamsen 2011: MD -1.00 (95% CI -2.27 to 0.27), n=38 (hypnosis 19, relaxation 19); Stam 1984: MD not reported, n=27 (hypnosis 12, relaxation 15).
2 studies · 65 participants
GRADE not reported
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Habit reversal treatment led to lower pain intensity compared with waiting-list control; GRADE not reported.
1 finding from 1 review
Treatment failure (annual failure rate) · Children (aged 3-5.5 years) with early childhood caries in anterior primary teeth (>=2 carious surfaces), no pulp therapy
Zirconia crowns failed less than composite strip crowns (3.3% vs 15% annual failure) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review