Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,262 questions · 2,405 findings · 248 reviews · Headline outcomes only

No studies found 507 · 21.1%GRADE not reported 93 · 3.9%Very low 657 · 27.3%Low 708 · 29.4%Moderate 387 · 16.1%High 53 · 2.2%

Music‐based therapeutic interventions vs usual care or other activities

Emotional well‐being including quality of life · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Mood disturbance or negative affect: depression · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Mood disturbance or negative affect: anxiety · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Behavioural problems: agitation or aggression · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Behavioural problems: overall · people with dementia (all resided in institutional settings)
2 findings from 1 review

Music‐based therapeutic interventions vs usual care or other activities

Social behaviour: music vs other activities · people with dementia (all resided in institutional settings)
2 findings from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: episodes of re‐bleeding over 10 days All treatments (topical and oral) · adults with nasal haemorrhage (epistaxis)

Tranexamic acid probably leads to lower control of epistaxis: episodes of re‐bleeding over 10 days All… compared with placebo plus usual care or usual care alone (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: episodes of re‐bleeding over 10 days Oral treatment only · adults with nasal haemorrhage (epistaxis)

Tranexamic acid probably leads to lower control of epistaxis: episodes of re‐bleeding over 10 days Oral… compared with placebo plus usual care or usual care alone (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: episodes of re‐bleeding over 10 days Topical application (10% gel) only · adults with nasal haemorrhage (epistaxis)

Tranexamic acid showed no clear difference in control of epistaxis: episodes of re‐bleeding over 10 days Topical… compared with placebo plus usual care or usual care alone (low certainty).

1 finding from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: time to stop initial bleeding (proportion of patients whose bleeding is controlled in ≤ 30 minutes) · adults with nasal haemorrhage (epistaxis)

Tranexamic acid showed no clear difference in control of epistaxis: time to stop initial bleeding (proportion of… compared with placebo plus usual care or usual care alone (low certainty).

1 finding from 1 review

Tranexamic acid vs placebo + standard care

Severity of re‐bleeding: proportion of patients requiring blood transfusion within 10 days · adults with nasal haemorrhage (epistaxis)

Tranexamic acid showed no clear difference in severity of re‐bleeding: proportion of patients requiring blood… compared with placebo plus usual care or usual care alone (low certainty).

1 finding from 1 review