Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,018 questions · 3,100 findings · 369 reviews · Headline outcomes only

No studies found 774 · 25%GRADE not reported 108 · 3.5%Very low 727 · 23.5%Low 840 · 27.1%Moderate 474 · 15.3%High 177 · 5.7%

Standard‐dose adjuvant radiotherapy alone vs adjuvant chemoradiotherapy

Voice (Voice Handicap Index) · patients with HPV‐positive oropharyngeal carcinoma who have received minimally invasive transoral surgery

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Severe exacerbations requiring hospitalisation over the study period · Children from minority groups with doctor diagnosed asthma

The intervention showed no clear difference in severe exacerbations requiring hospitalisation over the study period (low certainty).

1 finding from 1 review

Intervention not reported

Number of participants who had one or more exacerbation of the study period · Adults from minority groups with doctor diagnosed asthma

It is very uncertain whether the intervention changes number of participants who had one or more exacerbation of the study… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants requiring oral corticosteroids over the study period · Adults from minority groups with doctor diagnosed asthma

It is very uncertain whether the intervention changes number of participants requiring oral corticosteroids over the study… (very low certainty).

1 finding from 1 review

Intervention not reported

Severe exacerbations requiring hospitalisation over the study period · Adults from minority groups with doctor diagnosed asthma

It is very uncertain whether the intervention changes severe exacerbations requiring hospitalisation over the study period (very low certainty).

1 finding from 1 review

External beam radiotherapy (EBRT) plus transarterial chemoembolisation (TACE) vs TACE alone

Mortality Number of deaths at maximum · participants with unresectable hepatocellular carcinoma

External beam radiotherapy (EBRT) plus transarterial… may leads to lower all‐cause mortality (at maximum 1‐year compared with TACE alone (low certainty).

1 finding from 1 review

External beam radiotherapy (EBRT) plus transarterial chemoembolisation (TACE) vs TACE alone

Complete response plus partial response Length of · participants with unresectable hepatocellular carcinoma

External beam radiotherapy (EBRT) plus transarterial… may leads to higher complete response plus partial response Length of compared with TACE alone (low certainty).

1 finding from 1 review

External beam radiotherapy (EBRT) plus transarterial chemoembolisation (TACE) vs TACE alone

Elevated total bilirubin Length of · participants with unresectable hepatocellular carcinoma

It is very uncertain whether external beam radiotherapy (EBRT) plus transarterial… changes elevated total bilirubin Length of compared with TACE alone (very low certainty).

1 finding from 1 review

External beam radiotherapy (EBRT) vs chemoembolisation

All‐cause mortality (at 1 year) · participants with unresectable hepatocellular carcinoma

It is very uncertain whether external beam radiotherapy (EBRT) changes all‐cause mortality (at 1 year) compared with transarterial chemoembolisation (TACE) (very low certainty).

1 finding from 1 review