Synbiotic vs control
- Synbiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2022 · Cochrane Headline outcomes onlyno estimate extracted6 studies · 907 participantsLow
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The review found no eligible studies for this question.
About 57% of children with caries in LMICs had good brushing habits (pooled prevalence 0.569, 95% CI 0.354 to 0.771; 7 studies; very high heterogeneity; not GRADE-rated).
About 45% of children with caries in LMICs had mothers with secondary or higher education (pooled prevalence 0.450, 95% CI 0.330 to 0.572; 7 studies; not GRADE-rated).
Caregiver help with tooth brushing was associated with 65% lower odds of dental caries (OR 0.35, 95% CI 0.13 to 0.93; 3 studies; very high heterogeneity; not GRADE-rated).
About 44% of children in LMICs had access to or had visited dental services (pooled prevalence 0.444, 95% CI 0.277 to 0.618; 5 studies; not GRADE-rated).
About 35% of children with caries in LMICs were of middle SES (pooled prevalence 0.353, 95% CI 0.180 to 0.550; 7 studies; not GRADE-rated).
About 25% of children with caries in LMICs were of high SES (pooled prevalence 0.245, 95% CI 0.162 to 0.339; 5 studies; not GRADE-rated).
Sugary drinks/sweets consumption was associated with about twice the odds of dental caries in LMIC children (OR 2.04, 95% CI 1.59 to 2.60; 7 studies; not GRADE-rated).
In prospective cohorts, adults with 11-16 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 2.27, 95% CI 1.55 to 3.32; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
In prospective cohorts, the multivariable-adjusted HR for all-cause mortality in edentulous adults (0 teeth) vs adults with 1-32 teeth was 1.30 (95% CI 1.21 to 1.40; 7 studies, I2=20%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
In prospective cohorts, adults with 17-24 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 1.73, 95% CI 1.22 to 2.45; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
In prospective cohorts, the crude HR for all-cause mortality in adults with 0-19 teeth vs adults with 20-32 teeth was 2.47 (95% CI 2.40 to 2.54; 2 studies, I2=0%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
Each additional lost tooth was associated with a multivariable-adjusted HR of 1.02 (95% CI 1.01 to 1.03) for all-cause mortality (11 studies, I2=89%), statistically significant; GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
In prospective cohorts, adults with 1-19 teeth had a higher cumulative incidence of all-cause mortality than adults with 20-32 teeth (RR 1.76, 95% CI 1.41 to 2.19; 8 cohort studies, I2=94%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
In prospective cohorts, the multivariable-adjusted HR for ACVD-related events in edentulous adults (0 teeth) vs adults with 1-32 teeth was 1.21 (95% CI 1.07 to 1.36; 5 studies, I2=35%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
In prospective cohorts, the crude HR for ACVD-related events in adults with 0-19 teeth vs adults with 20-32 teeth was 2.27 (95% CI 1.50 to 3.43; 1 study, I2 not applicable (single study)); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
In prospective cohorts, edentulous adults (0 teeth) had a higher cumulative incidence of ACVD-related events than adults with 20-32 teeth (RR 2.65, 95% CI 1.77 to 3.98; 2 cohort studies, I2=60%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).